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Angiofollikuläre lymphatische Hyperplasie mit Plasmozytom und Polyneuropathie: Ein Fallbericht mit immunhistochemischer Untersuchung

Castleman's disease with plasmacytoma and polyneuropathy: A case report with immunohistological study

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Summary

A rare case of a 43-year-old man with polyneuropathy, monoclonal gammopathy, myeloma and Castleman's disease of plasma cell type was diagnosed. Immunohistological examination of the lymph node with Castleman's disease showed polyclonal binding while the myeloma was monoclonal containing IgA with λ-light chains. At the immunoelectrophoresis IgA/IgA paraprotein was demonstrated. The possible pathogenetical relationship between polyneuropathy and plasmacytoma as well as Castleman's disease will be discussed.

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Abbreviations

AFLH:

Angiofollikuläre lymphatische Hyperplasie

AFP:

Alpha-Foetoprotein

CEA:

Carcinoembryonaler Antigen

HIV:

Human immunodeficiency virus

PEP:

polyneuropathy, edema, plasmacelldyscrasia

POEMS:

polyneuropathy, organomegaly, endocrinopathy, M-protein, skin lesions

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Authors and Affiliations

  1. Pathologisches Institut der Universität Bonn, Germany

    O. Dworák, K. Tschubel, H. Zhou & M. Meybehm

  2. Abteilung für Klinische Pathologie in der Chirurgischen Universitätsklinik Erlangen Maximiliansplatz, D-8520, Erlangen

    O. Dworák

Authors
  1. O. Dworák
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  2. K. Tschubel
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  3. H. Zhou
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  4. M. Meybehm
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Dworák, O., Tschubel, K., Zhou, H. et al. Angiofollikuläre lymphatische Hyperplasie mit Plasmozytom und Polyneuropathie: Ein Fallbericht mit immunhistochemischer Untersuchung. Klin Wochenschr 66, 591–595 (1988). https://doi.org/10.1007/BF01720834

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  • DOI: https://doi.org/10.1007/BF01720834

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