Summary
Information and specimens of blood collected during a diabetic survey of the population of Arbroath have been used to study plasma cholesterol, NEFA andβ-lipoprotein in diabetes and cardiovascular disease. The mean levels of post-prandial plasma cholesterol,β-lipo — protein and blood glucose are significantly raised in persons with histories of cardiovascular disease compared with those without. In the family history of patients with cardiovascular disease, diabetes was found more often than in the family history of normal persons. This differnce was statistically significant.
Résumé
Les observations et les prélèvements de sang, recueillis au cours d'une enquête sur le diabète dans la population d'Arbroath, ont servi à étudier la teneur du plasma en cholestérol, NEFA etβ-lipoprotéine dans le diabète et les maladies eardio-vasculaires. Les taux moyens post-prandiaux de cholestérol etβ-lipoprotéine plasmatiques et de glucose sanguin sont significativement augmentés chez les personnes présentant une histoire d'atteinte cardiovasculaire par comparaison avec celles qui n'en présentaient pas. Le diabète était trouvé plus souvent dans l'histoire familiale des patients atteints de maladie cardiovasculaire que dans celle des sujets normaux. Cette différence est statistiquement significative.
Zusammenfassung
Bei einer epidemiologischen Untersuchung über das Vorkommen von Diabetes in der Bevölkerung von Arbroath wurden Blutproben auf ihren Gehalt an Cholesterin, NEFA undβ-Lipoproteine im Hinblick auf Diabetes und Krankheiten der Arterien untersucht. Die postprandialen Durchschnittswerte des Plasma-Cholesterin, derβ-Lipoproteine und der Glucose sind bei Personen, bei denen in der Anamnese kardiovasculäre Störungen vorkommen, statistisch höher als bei denen, in deren Anamnese dies nicht der Fall ist. In den Familien von Patienten mit kardiovasculären Krankheiten liegt Diabetes öfter vor als in gesunden Familien. Dieser Unterschied ist statistisch gesichert.
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Mitchell, F.L., Pearson, J. & Strauss, W.T. Plasma lipids and glucose in normal health, diabetes and cardiovascular disease. Diabetologia 4, 105–108 (1968). https://doi.org/10.1007/BF01212540
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DOI: https://doi.org/10.1007/BF01212540