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Furosemide, mithramycin, and salmon calcitonin in hypercalcemia

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Abstract

Twenty-nine patients with acute hypercalcemia secondary to carcinoma, myeloma and parathyroid adenoma have been treated with large doses of furosemide, mithramycin, or salmon calcitonin perfusion. With furosemide administration the treatment was successful in 6 of 10 patients. Furosemide was injected intravenous ly at the rate of 125 mg every 3 hours. With mithramycin perfusion only 2 of 8 patients have a rectum of the serum calcium levels to normal. With salmon thyrocalcitonin 3 of 10 patients obtained a good result. It can be interesting to suggest the association of furosemide and salmon calcitonin infusion to treat hypercalcemia of myeloma.

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References

  1. Duarte, C. G.: Effects of furosemide and ethacrynic acid on the renal clearance of phosphate ultrafiltrable calcium and magnesium. Clin. Res. Proc. 15, 357 (1967)

    Google Scholar 

  2. Eknoyan, G., Suki, W. N., Martinez-Maldonado, M.: Effect of diuretics on urinary excretion of phosphate, calcium and magnesium in thyroparathyroidectomised dogs. J. Lab. Clin. Med. 76, 257 (1970)

    Google Scholar 

  3. Fillastre, J. P., Humbert, G., Leroy J.: Treatment of acute hypercalcemia with furosemide. Current Ther. Res. 15, 641 (1973)

    Google Scholar 

  4. Fillastre, J. P., Maitrot, J., Canonne, M. A., Gray, H., Jeanne, C., Bastit, P., Bourgeois, T.: Renal function and alterations in plasma electrolyte levels in normocalcaemic and hypercalcaemic patients with malignant diseases, given an intravenous infusion of mithramycin. Chemotherapy (in press)

  5. Richet, G., Ardaillou, R., Meyerovitch, A., Fillastre, J. P.: Effets de la thyrocalcitonine sur l'excrétion rénale du phosphore, du calcium, du sodium et du chlore. Actual. Néphrol. Hôp. Necker, Paris: Flammarion, 1968, pp. 287–300

    Google Scholar 

  6. Suki, W. N., Yium, J. J., von Minden, M., Saller, Hebert C., Eknoyan, G., Martinez-Maldonado, M.: Acute treatment of hypercalcaemia with furosemide. New Engl. J. Med. 283, 836 (1970)

    Google Scholar 

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Authors and Affiliations

  1. Services de Néphrologie, Réanimation Médicale et Biochimie, Hôpital Charles Nicolle, Rouen, France

    J. P. Fillastre, G. Humbert, J. Leroy, J. Maitrot, P. Deshayes & M. A. Canonne

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  1. J. P. Fillastre
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  2. G. Humbert
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  3. J. Leroy
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  4. J. Maitrot
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  5. P. Deshayes
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  6. M. A. Canonne
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Fillastre, J.P., Humbert, G., Leroy, J. et al. Furosemide, mithramycin, and salmon calcitonin in hypercalcemia. Europ. J. Intensive Care Med 1, 185–188 (1975). https://doi.org/10.1007/BF00624436

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  • DOI: https://doi.org/10.1007/BF00624436

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