Summary
Chloroform-methanol extracts of lyophilized milk, of commercially available dried milk or baby food and of casein digests were tested for opioid activity on the guinea-pig ileum longitudinal muscle-myenteric plexus preparation. Compounds with opioid activity — which proved to be resistant to peptidases — were detected in certain batches of baby food, casein digest, and cow milk in considerably varying amounts.
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References
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Brantl, V., Teschemacher, H. A material with opioid activity in bovine milk and milk products. Naunyn-Schmiedeberg's Arch. Pharmacol. 306, 301–304 (1979). https://doi.org/10.1007/BF00507118
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DOI: https://doi.org/10.1007/BF00507118