Summary
This communication describes the presence of 1-methyl-β-carboline (harman) in the hypophysiotropic area of the hypothalamus which incorporates the arcuate nucleus. Diethyl ether extracts of boratebuffered arcuate homogenates were subjected to silica column chromatography and thin-layer chromatography (TLC). Identification of the β-carboline was accomplished by use of fluorescent spectrometry, gas chromatography (GC), mass spectrometry (MS) and combined gas chromatography-mass spectrometry (GC-MS).
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Shoemaker, D.W., Cummins, J.T., Bidder, T.G. et al. Identification of harman in the rat arcuate nucleus. Naunyn-Schmiedeberg's Arch. Pharmacol. 310, 227–230 (1980). https://doi.org/10.1007/BF00499914
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DOI: https://doi.org/10.1007/BF00499914