Summary
In unrestrained, unanaesthetized cats a mass discharge can be recorded from the medial longitudinal fasciculus at mesencephalic level on single shock stimulation of the VIIIth cranial nerve. Latency measurements indicate that the potential is due to monosynaptic excitation of second order vestibular neurones. The changes in amplitude of this response have been investigated during physiological sleep and wakefulness. In particular the monosynaptic response is not affected during quiet wakefulness and synchronized sleep, nor during desynchronized sleep in the absence of ocular movements. A depression of the orthodromic potential, however, occurs during the transient orienting reaction elicited by arousing stimulations, and also during desynchronized sleep at the time of the rapid eye movements. The nature of this depression is discussed.
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This investigation was supported by PHS research grant NB 05695-03 from the National Institute of Neurological Diseases and Blindness, N.I.H., Public Health Service, U.S.A.
Fellow of IBRO/Unesco.
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Lenzi, G.L., Pompeiano, O. & Satoh, T. Input-output relation of the vestibular system during sleep and wakefulness. Pflugers Arch. 299, 326–333 (1968). https://doi.org/10.1007/BF00602908
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DOI: https://doi.org/10.1007/BF00602908