Summary
The effects of changes in extracellular potassium concentration on the membrane potential of mammalian spinal neurones in tissue culture have been studied. An increase of extracellular potassium caused a depolarization of the cell membrane which was proportional to the amount of potassium in the bathing fluid. The method of tissue culture provides a useful model for investigating the effects of variations in the extracellular ionic environment on the bioelectric activity of single cells of the mammalian central nervous system.
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Hösli, L., Andrès, P.F. & Hösli, E. Effects of potassium on the membrane potential of spinal neurones in tissue culture. Pflugers Arch. 333, 362–365 (1972). https://doi.org/10.1007/BF00586215
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DOI: https://doi.org/10.1007/BF00586215