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Determination of theophylline in serum by non-isotopic immunoassays (EMIT, SLFIA, NIIA) and HPLC — A comparative study

Bestimmung von Theophyllin in Serum mittels non-isotopic Immunoassays (EMIT, SLFIA, NIIA) und HPLC — Eine vergleichende Untersuchung

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Conclusion

All of the immunoassays tested were rapid and easy to perform. The precision of these tests was adequate and the results were comparable with those obtained by HPLC. The EMIT correlated best with HPLC and showed a high specificity. Normally encountered levels of other xanthines or uric acids apparently do not interfere with this assay.

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References

  1. Oellerich M (1980) In: Wettengel R (ed) Asthma-Therapie mit Theophyllin Optimierung durch Blutspiegel-Bestimmung. Dustri-Verlag Dr. Karl Feistle, München-Deisenhofen, pp 66–82

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  2. Staib AH, Schuppan D, Lissner R, Zilly W, v Bomhard G, Richter E (1980) Internat J Clin Pharmacol Therap Toxicol 18:500–502

    Google Scholar 

  3. Jusko WJ, Poliszczuk A (1976) Am J Hosp Pharm 33:1193–1196

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  4. Schuster R, Riedmann M, Zech K (1982) Hewlett Packard application note 232-21, in press

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Authors and Affiliations

  1. Institut für Klinische Chemie, Deutschland

    M. Oellerich, W. R. Külpmann & M. Beneking

  2. Zentrum für Innere Medizin und Dermatologie, Medizinische Hochschule, Karl-Wiechert-Allee 9, D-3000, Hannover 61, Germany

    G. W. Sybrecht

  3. Zentrum der Pharmakologie, Klinische Pharmakologie, Klinikum der J. W. Goethe-Universität, D-6000, Frankfurt/M., Germany

    A. H. Staib

  4. Hewlett Packard GmbH, D-7517, Waldbronn, Germany

    R. Schuster

Authors
  1. M. Oellerich
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  2. W. R. Külpmann
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  3. M. Beneking
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  4. G. W. Sybrecht
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  5. A. H. Staib
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  6. R. Schuster
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Oellerich, M., Külpmann, W.R., Beneking, M. et al. Determination of theophylline in serum by non-isotopic immunoassays (EMIT, SLFIA, NIIA) and HPLC — A comparative study. Z. Anal. Chem. 311, 355–356 (1982). https://doi.org/10.1007/BF00481724

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  • DOI: https://doi.org/10.1007/BF00481724

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