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A new sensitive gas-chromatographic method for the determination of fenfluramine in biological specimens

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Summary

A new analytical procedure is described for the determination of fenfluramine and norfenfluramine in biological specimens. Fenfluramine and norfenfluramine are converted to the trichloroacetyl derivatives, separated on a 3% OV 17 — Chromosorb Q glass column and measured by ECD. The rapidity, sensitivity and specificity of the technique fulfil all the requirements for routine clinical use.

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Authors and Affiliations

  1. Istituto di Ricerche Farmacologiche ‘Mario Negri’, Milano, Italy

    G. Belvedere, G. Tognoni & P. L. Morselli

Authors
  1. G. Belvedere
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  2. G. Tognoni
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  3. P. L. Morselli
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Belvedere, G., Tognoni, G. & Morselli, P.L. A new sensitive gas-chromatographic method for the determination of fenfluramine in biological specimens. Eur J Clin Pharmacol 5, 62–64 (1972). https://doi.org/10.1007/BF00560898

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  • DOI: https://doi.org/10.1007/BF00560898

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