Abstract
A mathematical model has been developed by performing a non-linear regression analysis to simulate the fermentation process of glucose to lactic acid by considering the product-inhibition situation and substrate requirement for cell maintenance. To account for such an effect a toxic power (n) and a cell-maintenance factor (m) have been incorporated onto the model. In the present study the order of inhibition was calculated to be 0.88. Moreover, a small value for the cell maintenance factor (m) indicates that the effect of this parameter on the lactic acid fermentation is not appreciable and hence can be neglected.
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Kumar Dutta, S., Mukherjee, A. & Chakraborty, P. Effect of product inhibition on lactic acid fermentation: simulation and modelling. Appl Microbiol Biotechnol 46, 410–413 (1996). https://doi.org/10.1007/BF00166238
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DOI: https://doi.org/10.1007/BF00166238