Abstract
The healing of a diaphyseal tibia fracture was followed in the rat. Callus formation, blood flow and Sr-85 uptake were assessed by a ratio comparison of the fractured to the contralateral side. No correlation was found between blood flow and Sr-85 deposition in the callus and the adjacent bone of the same extremity. It is concluded that the deposition of a radiopharmaceutical in bone is primarily related to the presence of calcifiable organic bone matrix and only secondarily to the bone formation rate and to variations in the local blood flow.
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Schümichen, C., Mundriziewski, L., Tischler, E. et al. Relationship between blood flow and radiostrontium uptake in the healing bone fracture. Eur J Nucl Med 4, 413–417 (1979). https://doi.org/10.1007/BF00300837
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DOI: https://doi.org/10.1007/BF00300837