Summary
The mean percentage of autologous and ‘active’ rosette-forming T lymphocytes was determined in peripheral blood of 21 untreated patients with nonmetastatic squamous-cell lung carcinoma. The percentage of active rosettes was slightly lower in the patients than in normal individuals, but the difference was not statistically significant. No difference was found for autologous rosettes between patients and controls. No correlation was demonstrable between autologous and active rosettes in this group of patients (r=0.055).
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References
Bainbridge ET, Ford CHJ, Newman CE, Carter AB (1977) Active T cells in breast cancer. Lancet 2:1353.
Caraux J, Thierry C, Estève C, Flores G, Ladise R, Serrou B (1979a) Human autologous rosettes. I. Mechanism of binding of autologous erythrocytes by T cells. Cell Immunol. 45:36.
Caraux J, Thierry C, Serrou B (1979b) Human autologous rosettes. II. Prognostic significance of variations in autologous rosette forming cells in the peripheral blood of cancer patients. J Natl Cancer Inst 63:593.
Charreire J, Bach JF (1974) Self and not self. Lancet 2:299.
Dewar AE, Stuart AE, Parker AC, Wilson C (1974) Rosetting cells in auto-immune haemolytic anaemia. Lancet 2:519.
Felsburg PJ, Edelman R, Gilman RH (1976) The active E rosette test: Correlation with delayed cutaneous hypersensitivity. J Immunol 116:1110.
Fudenberg HH, Wybran J, Robbins D (1975) T-rosette-forming cells, cellular immunity and cancer. N Engl J Med 292:475.
Gluckman JC, Montambault P (1975) Spontaneous autorosette-forming cells in man. A marker for a subset population of T lymphocytes? Clin Exp Immunol 22:302.
Horowitz S, Groshong T, Albrecht R, Hong R (1975) The ‘active’ rosette test in immunodeficiency diseases. Clin Immunol Immunopathol 4:405.
Kaplan J (1975) Human T lymphocytes form rosettes with autologous and allogeneic human red blood cells. Clin Immunol Immunopathol 3:471.
Kerman RH, Smith R, Stefani SS, Ezdinli E (1976) Active T-rosette forming cells in the peripheral blood of cancer patients. Cancer Res 36:3274.
Lambermont M, Wybran J, Govaerts A (1977) Human autologous and allogeneic rosettes. J Immunol Methods 15:157.
Lang JM, Bigel P, Oberling F, Mayer S (1977) Normal active rosette-forming-cells in untreated patients with Hodgkin's disease. Biomedicine 27:322.
Sandilands GP, Gray K, Cooney A, Browning JD, Anderson JR (1975) Formation of auto-rosettes by peripheral blood lymphocytes. Clin Exp Immunol 22:493.
Wybran J (1977) Various subpopulations of autologous T rosettes in cancer patients (abstract). Cancer Immunol Immunother [Suppl] 3:S2.
Wybran J, Fudenberg HH (1973) Thymus-derived rosette-forming cells in various human disease states: cancer, lymphoma, bacterial and viral infections and other diseases. J Clin Invest 52:1026.
Yu DTY (1975) Lymphocyte subpopulations. Human red blood cell rosettes. Clin Exp Immunol 20:311.
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Lang, J.M., Hasselmann, J.P., Roeslin, N. et al. Comparative study of autologous and ‘active’ rossette-forming T lymphocytes in untreated patients with nonmetastatic squamous-cell lung carcinoma. Cancer Immunol Immunother 8, 45–47 (1980). https://doi.org/10.1007/BF00206353
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DOI: https://doi.org/10.1007/BF00206353