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Low dose irradiation for limb salvage in malignant bone tumours

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Summary

We have assessed the value of adding low dose radiotherapy to preoperative chemotherapy in 20 patients with high grade malignant bone tumours. Histology of the resected specimens showed a considerable tumouricidal effect and a distinct capsule enclosing the extraosseous part of the tumour. There were no serious side effects.

Résumé

Nous avons étudié sur le plan clinique et anatomo-pathologique, chez 20 malades atteints de tumeurs osseuses de haut degré de malignité, la valeur de la radiothérapie à la dose de 30 Gy en complément de la chimiothérapie pré-opératoire. L'histologie des pièces réséquées chirurgicalement a montré un effet tumoricide considérable et l'encapsulement de la partie extra-osseuse de la tumeur. La radiothérapie n'a pas déterminé d'effets secondaires fâcheux. Elle paraît donc indiquée pour la conservation des membres en cas de tumeurs osseuses de haut degré de malignité.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Nagasaki University School of Medicine, 7-1 Sakamoto-machi, 853, Nagasaki City, Japan

    T. Hirano, K. Iwasaki, T. Kumashiro & R. Suzuki

Authors
  1. T. Hirano
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  2. K. Iwasaki
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  3. T. Kumashiro
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  4. R. Suzuki
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Hirano, T., Iwasaki, K., Kumashiro, T. et al. Low dose irradiation for limb salvage in malignant bone tumours. International Orthopaedics 15, 381–385 (1991). https://doi.org/10.1007/BF00186884

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  • DOI: https://doi.org/10.1007/BF00186884

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