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Combined-modality treatment for stage IIIa (n2) non-small cell lung cancer: a national cancer institute intergroup study

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Abstract

Induction chemotherapy plus radiotherapy followed by surgery, evaluated in a number of phase II studies, is an effective treatment for patients with stage III A non-small cell lung cancer (NSCLC). The ongoing phase III National Cancer Institute Intergroup study is evaluating concurrent chemotherapy (cisplatin + etoposide)/radiotherapy followed by either surgery or additional radiotherapy followed by 2 additional cycles of chemotherapy in patients with stage III A disease. This study will help define the role of surgery and radiotherapy as part of the multimodality therapy of locoregional advanced NSCLC.

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Authors and Affiliations

  1. The Johns Hopkins Oncology Center, Room 147, 600 N. Wolfe St., 21287-8936, Baltimore, MD, USA

    David S. Ettinger

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  1. David S. Ettinger
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Work presented at the 13th Bristol-Myers Squibb Nagoya International Cancer Treatment Symposium, “Strategic Cross Talk between Major Oncology Groups/Clinical Pharmacology in Cancer Chemotherapy”, 17–18 October 1997, Nagoya, Japan

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Ettinger, D.S. Combined-modality treatment for stage IIIa (n2) non-small cell lung cancer: a national cancer institute intergroup study. Cancer Chemother Pharmacol 42 (Suppl 1), S71–S74 (1998). https://doi.org/10.1007/s002800051083

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