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Effect of acetylsalicylic acid on secondary metabolism ofCatharanthus roseus tumor suspension cultures

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Summary

Addition of various concentrations (0.5–20 mM) of acetylsalicylic acid (ASA) to tumor lines ofCatharanthus roseus cultivatedin vitro and requiring corn starch as carbon source, produced remarkable effects on secondary metabolite production. An increase of 505% total alkaloids per culture (cells plus liquid medium), 1587% total phenolics (liquid medium), 612% total furanocoumarins (liquid medium) and 1476% total anthocyanins (liquid medium) was detected. 1 mM ASA in combination with other elicitors, such as homogenates ofAspergillus fumigatus or trans-cinnamic acid, did not further increase the metabolite content substantially. The results suggest that ASA could act as a new biotic elicitor of metabolite production inC. roseus cell suspension culture.

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References

  • Davis KR, Hahlbrock K (1987) Plant Physiology 85: 1286–1290

    Google Scholar 

  • Do CB, Cormier F (1990) Plant Cell Reports 9:143–146

    Google Scholar 

  • Do CB, Cormier F (1991) Plant Cell Tissue and Organ Culture 27: 169–174

    Google Scholar 

  • Do CB, Cormier F (1991) Plant Cell Reports 9:500–504

    Google Scholar 

  • Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F (1956) Analytical Chemistry 28: 350–356

    Google Scholar 

  • Fries L (1984) Canadian Journal of Botany 62: 1616–1620

    Google Scholar 

  • Godoy-Hernández G, Loyola-Vargas VM (1991) Plant Cell Reports 10: 537–540

    Google Scholar 

  • Hirasuna TJ, Shuler ML, Lackney VK, Spanswick RM (1991) Plant Science 78: 107–120

    Google Scholar 

  • Kaihara S, Watanabe K, Takimoto A (1981) Plant Cell Physiology22: 819–825

    Google Scholar 

  • Khurana JP, Maheshwari SC (1978) Plant Science Letters 12: 127–131

    Google Scholar 

  • Khurana JP, Maheshwari SC (1983) Plant Cell Physiology 24: 907–912

    Google Scholar 

  • Klessig DF, Malamy J (1994) Plant Molecular Biology 26: 1439–1458

    Google Scholar 

  • Knobloch K-H, Bast G, Berlin J (1982) Phytochemistry 21: 591–594

    Google Scholar 

  • Kombrink E, Hahlbrock K (1986) Plant Physiology 81: 216–221

    Google Scholar 

  • Kumar S, Nanda KK (1981) Biologia Plantarum 23: 321–327

    Google Scholar 

  • Lee H, León J, Raskin I (1995) Proceedings of the National Academy of Science (USA) 92: 4076–4079

    Google Scholar 

  • Lee TT, Skoog F (1996) Physiologia Plantarum 18: 386–402

    Google Scholar 

  • Leslie CA, Romani RJ (1986) Plant Cell Reports 5: 144–146

    Google Scholar 

  • Phillips GC, Collins GB (1979) Crop Science 19: 59–64

    Google Scholar 

  • Raskin I (1992) Annual Review of Plant Physiology and Plant Molecular Biology 43: 439–463

    Google Scholar 

  • Reynolds T (1978) Annals of Botany 42: 419–427

    Google Scholar 

  • Saint-Pierre B, Miville L, Dion P (1984) Canadian Journal of Botany 62: 729–734

    Google Scholar 

  • Seitz HU, De Luca V, Kurz WGW (1989) Plant Cell Tissue and Organ Culture 18: 71–78

    Google Scholar 

  • Watanabe K, Takimoto A (1979) Plant Cell Physiology 20: 874–850

    Google Scholar 

Download references

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Authors and Affiliations

  1. Departamento de Biología Experimental, División de Biología Vegetal, Centro de Investigación Científiíca de Yucatán, Apartado Postal 87, Cordemex, 97310, Yucatán, México

    Gregorio Godoy-Hernández & Victor M. Loyola-Vargas

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  1. Gregorio Godoy-Hernández
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  2. Victor M. Loyola-Vargas
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Communicated by F. Constabel

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Godoy-Hernández, G., Loyola-Vargas, V.M. Effect of acetylsalicylic acid on secondary metabolism ofCatharanthus roseus tumor suspension cultures. Plant Cell Reports 16, 287–290 (1997). https://doi.org/10.1007/BF01088282

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  • DOI: https://doi.org/10.1007/BF01088282

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