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Ultrastructural observations on silver deposition in the choroid plexus of a patient with argyria

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Summary

A 72-year-old woman developed generalized argyria after prolonged intranasal application of a colloidal silver solution. The brain parenchyma, including several infarcts, was free of silver, but the choroid plexus showed silver deposited in the basal lamina, the stroma including calcified bodies, and occasionally within a mesenchymal cell of the choroid plexus stroma. The basal lamina beneath the choroidal epithelium was most affected. The silver granules appeared solid and free of any limiting membrane.

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Authors and Affiliations

  1. Division of Neuropathology, Indiana University School of Medicine, Indianapolis, Indiana

    Hans H. Goebel & Jans Muller

  2. Neuropathologische Abteilung, Nervenkliniken der Universität Göttingen, von Siebold-Straße 5, D-3400, Göttingen, Bundesrepublik Deutschland

    Hans H. Goebel

Authors
  1. Hans H. Goebel
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  2. Jans Muller
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Additional information

Supported by USPHS grants NS-04607 and NS-09797; and also a grant from The Children's Brain Diseases Foundation, San Francisco.

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Goebel, H.H., Muller, J. Ultrastructural observations on silver deposition in the choroid plexus of a patient with argyria. Acta Neuropathol 26, 247–251 (1973). https://doi.org/10.1007/BF00684434

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  • DOI: https://doi.org/10.1007/BF00684434

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