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Pineoblastoma with ganglionic and glial differentiation

Report of two cases

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Summary

Two cases of pineoblastoma in infants are reported. Both cases exhibited ganglionic and astrocytic differentiation, and one case also showed retinoblastomatous features. Divergent differentiation has been frequently reported in pineocytomas, but ganglionic and glial features in the highly malignant primitive pineoblastoma are unusual. These cases extend the concept of pineoblastoma and further confirm the differentiating potential of primary pineal parenchymal neoplasms.

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Author notes

  1. J. E. Trice

    Present address: Dept. of Neurology, University of California, San Diego School of Medicine, 92047, La Jolla, CA, USA

Authors and Affiliations

  1. Dept. of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA

    R. A. Sobel

  2. Dept. of Pathology, Rhode Island Hospital, Brown University School of Medicine, 02902, Providence, RI, USA

    J. E. Trice

  3. Dept. of Pathology, University of California Davis School of Medicine, 95817, Sacramento, CA, USA

    S. L. Nielsen & W. G. Ellis

Authors
  1. R. A. Sobel
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  2. J. E. Trice
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  3. S. L. Nielsen
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  4. W. G. Ellis
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Sobel, R.A., Trice, J.E., Nielsen, S.L. et al. Pineoblastoma with ganglionic and glial differentiation. Acta Neuropathol 55, 243–246 (1981). https://doi.org/10.1007/BF00691324

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  • DOI: https://doi.org/10.1007/BF00691324

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