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Amniotic fluid secretory immunoglobulin A in normal pregnancy and in pregnancy complicated by rhesus isoimmunization

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Summary

Amniotic fluid levels of secretory immunoglobulin A (S-IgA) were measured by simple radial immunodiffusion according to the method of Mancini using a monospecific antiserum against the human secretory component. We examined 256 samples from healthy pregnant women and 149 samples from mothers suffering from rhesus isoimmunization. During normal pregnancy amniotic fluid S-IgA increased significantly and showed a loose correlation with the phospholipid levels. This was not observed in pregnancies complicated by rhesus isoimmunization.

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Authors and Affiliations

  1. Clinic of Obstetrics and Gynecology, Wilhelm Pieck University, Doberaner Straße 142, GDR — 2500, Rostock, German Democratic Republic

    V. Briese, W. Straube & K. -H. Stark

  2. Institute of Physiological Chemistry, Wilhelm Pieck University, Leninallee 70, GDR — 2500, Rostock, German Democratic Republic

    J. Brock & U. Lorenz

Authors
  1. V. Briese
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  2. W. Straube
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  3. J. Brock
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  4. K. -H. Stark
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  5. U. Lorenz
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Briese, V., Straube, W., Brock, J. et al. Amniotic fluid secretory immunoglobulin A in normal pregnancy and in pregnancy complicated by rhesus isoimmunization. Arch. Gynecol. 233, 1–6 (1982). https://doi.org/10.1007/BF02110672

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  • DOI: https://doi.org/10.1007/BF02110672

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