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Photodynamic therapy for recurrent gynecologic malignancy: a report on 4 cases

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Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract.

4 patients with recurrent gynecological malignancy were treated photodynamically, 4 d after sensitisation with intravenous meso-tetra(hydroxyphenyl)chlorin (m-THPC) at a dose of 0.15 mg/kg bodyweight (total dose ranged from 12–15 mg). Light at 652 nm was derived from a KTP-Dye laser (Diasonic) and delivered superficially at a total light dose of 20 J/cm2 (power density of 100 mW/ sec). Within 24 h necrosis occurred which was restricted to the tumor area. There was serious bleeding occurred in 1 patient. All tumors responded to PDT, however woundhealing was significantly delayed and survival times were disappointingly short.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, University of Innsbruck, Anichstraße 35, A-6020 Innsbruck, , , , ,

    Elisabeth Krimbacher, A. G. Zeimet & C. Marth

  2. Department of Neurosurgery, University Hospital Innsbruck, Austria, , , , , , AT

    H. Kostron

Authors
  1. Elisabeth Krimbacher
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  2. A. G. Zeimet
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  3. C. Marth
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  4. H. Kostron
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Received: August 1998 / Accepted: 14 December 1998

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Krimbacher, E., Zeimet, A., Marth, C. et al. Photodynamic therapy for recurrent gynecologic malignancy: a report on 4 cases. Arch Gynecol Obstet 262, 193–197 (1999). https://doi.org/10.1007/s004040050249

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  • DOI: https://doi.org/10.1007/s004040050249

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