Summary
We have studied saccular and utricular otoconia from Shaker-1 and Shaker-2 mice by X-ray diffraction and scanning electron microscopy. In contrast to previous reports, we found that the crystals were composed of calcite rather than poly crystalline hydroxylapatite. These crystals were indistinguishable mineralogically and morphologically from normal mouse otoconia. The reported occurrence of hydroxylapatite otoconia in the Shaker mouse is probably false.
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Rouse, R.C., Johnsson, LG. A re-examination of otoconia from the Shaker mouse. Arch Otorhinolaryngol 242, 83–87 (1985). https://doi.org/10.1007/BF00464412
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DOI: https://doi.org/10.1007/BF00464412