Summary
Between 01. 01.1987 and 31.12.1990 a primary operation was performed on 126 patients in the Dept. of General Surgery, University of Marburg Hospital for primary hyperparathyroidism due to a parathyroid adenoma. Their clinically relevant data were prospectively documented. In 6 patients (4.8%) a total of 7 cystic parathyroid adenomas was found. While there was no difference in age- and sex-distribution, patients with cystic adenomas were found to have markedly higher serum parathormone and alkaline phosphatase levels than patients with solid adenomas. Calcium levels were similar in both groups. Cystic adenomas were much heavier than solid adenomas. A significant number of cystic adenomas was found to be displaced into the posterior mediastinum. The property of cystic parathyroid adenomas to be frequently located away from their usual anatomical position can make the intraoperative search for them difficult.
Zusammenfassung
Die klinisch relevanten Daten von 126 Patienten, die sich zwischen dem 1.1.1987 und dem 31.12.1990 wegen eines Nebenschilddrüsenadenoms an der Klinik für Allgemeinchirurgie der Philipps-Universität Marburg einer Erstoperation unterzogen, wurden prospektiv dokumentiert. Bei 6 Patienten (4,8 %) wurden insgesamt 7 zystische Adenome gefunden. Bei gleicher Alters- and Geschlechtsverteilung wiesen Patienten mit zystischen Adenomen deutlich höhere Serumspiegel für Parathormon and alkalische Phosphatase auf als die mit soliden Adenomen. Der Serumkalziumspiegel in den beiden Gruppen war nicht unterschiedlich. Zystische Adenome waren deutlich schwerer als solide Adenome. Ein erheblicher Anteil der zystischen Adenome war in das hintere Mediastinum verlagert. Die Eigenschaft zystischer Nebenschilddrüsenadenome, häufig nicht an den normalen anatomischen Positionen zu liegen, kann bei ihrer intraoperativen Suche zu Schwierigkeiten führen.
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Literatur
Albertson DA, Marshall RB, Jarman WT (1981) Hypercalcemic crisis secondary to a functioning parathyroid cyst. Am J Surg 141:175
Calandra DB, Shah KH, Prinz RA, Sullivan H, Hofmann C, Oslapas R, Ernst K, Lawrence AM, Paloyan E (1983) Parathyroid cysts: A report of eleven cases including two associated with hyperparathyroid crisis. Surgery 94:887
Chodack P, Attie JN, Groder MG (1965) Hypercalcemic crisis coincidental with hemorrhage in parathyroid adenoma. Arch Intern Med 116:416
Clark OH (1978) Parathyroid cysts. Am J Surg 135:395
Clark OH, Okerlund MD, Cavalieri RR, Greenspan FS (1979) Diagnosis and treatment of thyroid, parathyroid, and thyroglossal duct cysts. J Clin Endocrinol Metab 48:983
De Ridder VA, Brom HLF, Blok P (1986) Hyperparathyroidism due to primary cystic parathyroid adenoma. Neth J Surg 38:134
Ginsberg J, Young JEM, Walfish PG (1978) Parathyroid cysts —medical diagnosis and management. JAMA 240:1506
Kobayashi A, Kuma K, Matsuzuka F, Sugawara M (1989) Exacerbation of hypercalcemia after needle biopsy of a parathyroid cyst. Ann Intern Med 110:326
Koea JB, Shaw JHF (1988) Parathyroid cyst and hyperparathyroidism in Auckland. NZ Med J 101:655
Linos DA, Schoretsanitis G, Carvounis E (1989) Parathyroid cysts of the neck and mediastinum. Acta Chir Scand 155:211
Margolis IB, Wayne R, Organ CH (1975) Parathyroid cysts: Functional and mediastinal. Surgery 77:462
Pacini F, Antonelli A, Lari R, Gasperini L, Baschieri L, Pinchera A (1985) Unsuspected parathyroid cysts diagnosed by measurement of thyroglobulin and parathyroid hormone concentrations in fluid aspirates. Ann Intern Med 102:793
Rogers LA, Fitter B, Pette WPJ (1969) Parathyroid cyst and cystic degeneration of parathyroid adenoma. Arch Pathol 88:476
Rosenbaum GR, Morad A (1963) A review of parathyroid cysts. WV Med J 59:300
Rosenberg J, Orlando III R, Ludwig M, Pyrtek KJ (1982) Parathyroid cysts. Am J Surg 143:473
Verdonk CA, Edis AJ (1981) Parathyroid “double adenomas”: fact or fiction? Surgery 90:523
Wagner PK, Rothmund M (1983) Untersuchungen zur Korrelation von Tumorgewicht und typisch pathologischen Laborparametern beim primären und sekundären Hyperparathyreoidismus. Langenbecks Arch Chir 360:133
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Nies, C., Hasse, C., Zielke, A. et al. Zystische nebenschilddrüsenadenome : pathologisch-anatomische variante von epithelkörperchenadenomen oder krankheitsbild mit eigener bedeutung?. Langenbecks Arch Chir 377, 158–161 (1992). https://doi.org/10.1007/BF00184373
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DOI: https://doi.org/10.1007/BF00184373