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Zystische nebenschilddrüsenadenome : pathologisch-anatomische variante von epithelkörperchenadenomen oder krankheitsbild mit eigener bedeutung?

Cystic parathyroid adenomas: pathoanatomical variant of parathyroid adenomas or separate disease entity?

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Summary

Between 01. 01.1987 and 31.12.1990 a primary operation was performed on 126 patients in the Dept. of General Surgery, University of Marburg Hospital for primary hyperparathyroidism due to a parathyroid adenoma. Their clinically relevant data were prospectively documented. In 6 patients (4.8%) a total of 7 cystic parathyroid adenomas was found. While there was no difference in age- and sex-distribution, patients with cystic adenomas were found to have markedly higher serum parathormone and alkaline phosphatase levels than patients with solid adenomas. Calcium levels were similar in both groups. Cystic adenomas were much heavier than solid adenomas. A significant number of cystic adenomas was found to be displaced into the posterior mediastinum. The property of cystic parathyroid adenomas to be frequently located away from their usual anatomical position can make the intraoperative search for them difficult.

Zusammenfassung

Die klinisch relevanten Daten von 126 Patienten, die sich zwischen dem 1.1.1987 und dem 31.12.1990 wegen eines Nebenschilddrüsenadenoms an der Klinik für Allgemeinchirurgie der Philipps-Universität Marburg einer Erstoperation unterzogen, wurden prospektiv dokumentiert. Bei 6 Patienten (4,8 %) wurden insgesamt 7 zystische Adenome gefunden. Bei gleicher Alters- and Geschlechtsverteilung wiesen Patienten mit zystischen Adenomen deutlich höhere Serumspiegel für Parathormon and alkalische Phosphatase auf als die mit soliden Adenomen. Der Serumkalziumspiegel in den beiden Gruppen war nicht unterschiedlich. Zystische Adenome waren deutlich schwerer als solide Adenome. Ein erheblicher Anteil der zystischen Adenome war in das hintere Mediastinum verlagert. Die Eigenschaft zystischer Nebenschilddrüsenadenome, häufig nicht an den normalen anatomischen Positionen zu liegen, kann bei ihrer intraoperativen Suche zu Schwierigkeiten führen.

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Nies, C., Hasse, C., Zielke, A. et al. Zystische nebenschilddrüsenadenome : pathologisch-anatomische variante von epithelkörperchenadenomen oder krankheitsbild mit eigener bedeutung?. Langenbecks Arch Chir 377, 158–161 (1992). https://doi.org/10.1007/BF00184373

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  • DOI: https://doi.org/10.1007/BF00184373

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