Abstract
Angiosarcoma of the spleen is a very rare but highly malignant vascular neoplasm. So far only 140 cases have been reported. A 42-year-old patient is presented in which the radiologic imaging misled to the diagnosis of infiltrating echinococcosis. After splenectomy histological and immunohistochemical staining gave proof of metastatic angiosarcoma. The patient died three months later as a consequence of multiple organ dysfunction syndrome. The literature is reviewed in regard to clinical features, diagnosis and therapy.
Zusammenfassung
Mit ca. 140 publizierten Fällen stellt das Angiosarkom der Milz eine sehr seltene Erkrankung dar, die durch ihre hochmaligne Verlaufsform charakterisiert ist. Wir berichten über den Fall eines 42jährigen Patienten, dessen Befunde zunächst an eine disseminierte Echinokokkose denken ließen. Die richtige Diagnose konnte letztlich erst histologisch und immunhistochemisch nach Splenektomie gestellt werden. Der Patient verstarb 3 Monate nach Diagnosestellung bei ausgedehnter Lebermetastasierung. Anhand einer Literaturübersicht werden diagnostische und therapeutische Möglichkeiten diskutiert.
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Geißler, B., Lindemann, F., Fleischmann, R. et al. Angiosarkom der Milz. Langenbecks Arch Chiv 382, 226–230 (1997). https://doi.org/10.1007/BF02391871
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DOI: https://doi.org/10.1007/BF02391871