Skip to main content
Log in

Cytological findings in transrectal aspiration biopsy on hormone- and radio-treated carcinoma of the prostate

  • Published:
Virchows Archiv Aims and scope Submit manuscript

Summary

The study reports cytological findings in 63 cases of radio- and/or oestrogen-treated carcinoma of the prostate. The different effects of therapy on the tumor cells in the cytological smear are described and discussed.

An evaluation of the results, depending on the type of therapy, showed, that radio-treated tumors, due to the rapid and strong sclerosis of connective tissue, were less suitable for aspiration biopsy than hormone-treated tumors. Further, we were able to show that the effect of therapy in well-differentiated tumors is better than in poorly differentiated tumors.

Cytological examination of treated prostate carcinoma is a simple method, quickly carried out, repeatable several times, and of high diagnostic value.

Aspiration biopsy is most of all indicated for follow-up of the less well-differentiated and the hormone-treated carcinomas.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alken, C.E., Dhom, G., Hohbach, M., Sachse, D., Schröder, F.H., Straube, W.: Therapie des Prostatakarzinoms und Verlaufskontrolle (I). Urologe A (Berl.) 11, 216–220 (1972)

    CAS  Google Scholar 

  • Alken, C.E., Dhom, G., Straube, W., Braun, J.S., Kopper, B., Rehker, H.: Therapie des Prostatakarzinoms und Verlaufskontrolle (III). Urologe A (Berl.) 14, 112–116 (1975)

    CAS  Google Scholar 

  • Alken, C.E., Dhom, G., Straube, W., Schmidt-Hermes, H.-J., Moormann, J.G., Moeller, J.F.: Therapie des Prostatakarzinoms und Verlaufskontrolle (II). Urologe A (Berl.) 12, 191–197 (1973)

    CAS  Google Scholar 

  • Böhni, H.P.: Heilungsvorgänge in osteoplastischen Knochenmetastasen eines mit Oestrogenen behandelten Prostatakarzinoms. Z. Urol. 49, 30–47 (1956)

    PubMed  Google Scholar 

  • Egle, N., Spieler, P.: Zytologische und histologische Verlaufskontrollen beim hochvoltbestrahlten Prostatakarzinom. Helv. chir. Acta, 43, 337 (1976)

    CAS  PubMed  Google Scholar 

  • Esposti, P.L.: Cytologic diagnosis of prostatic tumors with the aid of transrectal aspiration biopsy. Acta cytol. (Philad.) 10, 182–186 (1966)

    CAS  Google Scholar 

  • Esposti, P.L.: Cytologic malignancy grading of prostatic carcinoma by transrectal aspiration biopsy. Scand. J. Urol. Nephrol. 5, 199–205 (1971)

    Article  CAS  PubMed  Google Scholar 

  • Fergusson, J.D., Franks, L.M.: The response of prostatic carcinoma to oestrogen treatment. Brit. J. Surg. 40, 422–428 (1952)

    Article  Google Scholar 

  • Franks, L.M.: Estrogen-treated prostatic cancer. Cancer (Philad.) 13, 490–501 (1960)

    Article  CAS  Google Scholar 

  • Franzén, S., Gierth, G., Zajicek, J.: Cytological diagnosis of prostatic tumours by transrectal aspiration biopsy: a preliminary report. Brit. J. Urol. 32, 193–196 (1960)

    Article  PubMed  Google Scholar 

  • Gaynor, E.P.: Zur Frage des Prostatakrebses. Virchows Arch. path. Anat. 301, 602–652 (1938)

    Article  Google Scholar 

  • Kastendieck, H., Altenähr, E.: Morphogenese und Bedeutung von Epithelmetaplasien in der menschlichen Prostata. Eine elektronen-mikroskopische Studie. Virchows Arch. Abt. A Path. Anat. and Histol. 365, 137–150 (1975a)

    Article  CAS  Google Scholar 

  • Kastendieck, H., Altenähr, E., Burchardt, P.: Zur Ultrastruktur des behandelten Prostatakarzinoms. Virchows Arch. Abt. A Path. Anat. and Histol. 366, 287–304 (1975 b)

    Article  CAS  Google Scholar 

  • Kastendieck, H., Altenähr, E., Burchardt, P., Becker, H., Franke, H.D., Klosterhalfen, H.: Morphologische und klinische Behandlungsergebnisse nach kombinierter Hormon- und Strahlentherapie des Prostatakarzinoms. Dtsch. med. Wschr. 101, 571–576 (1976)

    Article  CAS  PubMed  Google Scholar 

  • McMahon, M.J., Butler, A.V.J., Thomas, G.H.: Morphological responses of prostatic carcinoma to testosterone in organ culture. Brit. J. Cancer 26, 388–394 (1972)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Pellet, A., Grétillat, P.A.: Diagnostic cytologique des tumeurs prostatiques par ponction transrectale à l'aiguille fine de Franzén. Ann. Urol. 5, 247–252 (1971)

    CAS  Google Scholar 

  • Schenken, J.R., Burns, E.L., Kahle, P.J.: The effect of diethylstilbestrol and diethylstilbestrol-dipropionate on carcinoma of the prostate gland. II. Cytologic changes following treatment. J. Urol. (Baltimore) 48, 99–112 (1942)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Herrn Prof. Chr. Hedinger, Zürich, zu seinem 60. Geburtstag gewidmet

Rights and permissions

Reprints and permissions

About this article

Cite this article

Spieler, P., Gloor, F., Egle, N. et al. Cytological findings in transrectal aspiration biopsy on hormone- and radio-treated carcinoma of the prostate. Virchows Arch. A Path. Anat. and Histol. 372, 149–159 (1976). https://doi.org/10.1007/BF00427089

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00427089

Key words

Navigation