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Regional differences in the distribution of lipofuscin in Purkinje cell perikarya

A Quantitative pigmentarchitectonic study of the cerebellar cortex of senile albino rats

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Summary

The distribution of lipofuscin in the perikarya of Purkinje cells of vermal and hemispheric lobules has been determined quantitatively in 7 rats, 30–38 months old, by the point-counting method. On the basis of morphologically and statistically significant differences a pigmentarchitectonics of the cerebellar cortex is established. The Purkinje cells of lobule VIa (Larsell 1952) are extremely lipofuscin-rich. The Purkinje cells of the hemispheres, lobules V, VI b+c and VII contain considerable amounts of a finely granular lipofuscin, the Purkinje cells of lobules I–III and VIII–IX a a globular type of lipofuscin. The Purkinje cells of sublobule XI d c and X are lipofuscin-poor cells. Three types of lipofuscin have been identified in the light microscope.

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  1. Abt. Anatomie der RWTH Aachen, Melatener Str. 211, D-5100, Aachen, Federal Republic of Germany

    H. Heinsen

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Heinsen, H. Regional differences in the distribution of lipofuscin in Purkinje cell perikarya. Anat Embryol 161, 453–464 (1981). https://doi.org/10.1007/BF00316054

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