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Dynamic lung inflation during high frequency oscillation in neonates

  • Neonatology
  • Published:
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Abstract

The effects of high frequency oscillation (HFO) on dynamic lung inflation were examined in 22 neonates ventilated for respiratory disease. HFO was combined with conventional ventilation and a series of frequencies from 2–25 Hz was tested. Dynamic lung inflation was measured using a jacket plethysmograph which was converted to a measure of alveolar pressure using the complicance of the respiratory system obtained during conventional ventilation. The results showed an increase in dynamic lung inflation with frequency such that volume increased by 0.4 ml for each increase of 10 Hz. Alveolar pressure increased by 1.2 cm H2O for each increase of 10 Hz. Dynamic lung inflation also increased with increased volumes of oscillation.

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Abbreviations

CPAP:

continuous positive airways pressure

ET:

endotracheal

HFO:

high frequency oscillation

IPPV:

intermittent positive airways pressure

PEEP:

positive end expiratory pressure

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Authors and Affiliations

  1. Department of Neonatal Medicine and Surgery, City Hospital, Nottingham, UK

    E. W. Hoskyns, A. D. Milner & I. E. Hopkin

Authors
  1. E. W. Hoskyns
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  2. A. D. Milner
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  3. I. E. Hopkin
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Hoskyns, E.W., Milner, A.D. & Hopkin, I.E. Dynamic lung inflation during high frequency oscillation in neonates. Eur J Pediatr 151, 846–850 (1992). https://doi.org/10.1007/BF01957938

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  • DOI: https://doi.org/10.1007/BF01957938

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