Abstract
Blue light plays an important role in developmental control throughout nature. Thebli-4 gene ofNeurospora crassa, together withbli-3, al-1 andal-2, is rapidly inducible by blue light. Induction leads to a ninety-fold increase in transcription rate over the dark control level, and the gene therefore appears to be of prime importance in the blue-light induction pathway ofN. crassa. We describe the sequencing and analysis ofbli-4 and the 38 kDa protein it encodes. We show that the protein is very rapidly imported into the mitochondria and exhibits high homology with the family of short-chain alcohol dehydrogenases.
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Communicated by C. A. M. J. J. van den Hondel
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Bruchez, J.J.P., Eberle, J., Kohler, W. et al. bli-4, a gene that is rapidly induced by blue light, encodes a novel mitochondrial, short-chain alcohol dehydrogenase-like protein inNeurospora crassa . Molec. Gen. Genet. 252, 223–229 (1996). https://doi.org/10.1007/BF02173767
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DOI: https://doi.org/10.1007/BF02173767