Summary
Adult female guinea pigs received subcutaneous implants of diethylstilbestrol-cholestrol pellets which produced splenomegaly and increased numbers of splenic Kurloff cells. Latex spheres subsequently injected intravenously were not phagocytized by Kurloff cells within the lungs and spleen as examined with the electron microscope. This is considered as evidence that Kurloff cells are probably not phagocytic. The origin of these cells is discussed.
References
Barer, R., Joseph, S.: The effects of x-rays and radio-mimetic substances on Kurloff bodies. J. Physiol. 182, 1P-1P (1966)
Barer, R., Bradbury, S., Meek, G.: The nature of Kurloff bodies. J. Anat. 97, 140–141 (1963)
Berendsen, P., Telford, I.: A light and electron microscopic study of Kurloff bodies in the blood and spleen of the guinea pig. Anat. Rec. 156, 107–117 (1966)
Duplan, J.: Action d'une irradiation unique et totale de tout le corps sur les leucocytes a corps de Kurloff du sang périphérique du cobaye. C.R. Soc. Biol. 148, 974–975 (1954)
Foa, P., Carbone, T.: Beiträge zur Histologie und Physiopathologie der Milz der Säugetiere. Beitr. Path. Anat. 5, 227–252 (1889)
Frey, J.: The appearance of Kurloff's cells in azomide poisoning. Hematologica 18, 493–497 (1937)
Izard, J., Barrellier, M., Quillec, M.: No relationship between Foa's and Kurloff's body and erythrophagocytosis. Anat. Rec. 178, 516 (1974)
Kortelainen, L., Korhonen, L.: Kurloff cells. Acta Path. Microbiol. Scand. Sect. A84, 143–153, 154–164 (1976)
Kurloff, M.: Blood cells in splenectomized animals after one year life. (Russian). Vrach (St. Petersburg) 10, 515–518, 538–543 (1889)
Ledingham, J.: Sex hormones and Foa-Kurloff cell. J. Path. Bact. 50, 201–219 (1940)
Leinati, F.: Sull' origine nucleare dei corpi di Foa-Kurloff. Hematologica 13, 517–528 (1932)
Marshall, A., Swettenham, K., Vernon-Roberts, B., Revell, P.: Studies on the function of the Kurloff cell. Int. Arch. Allergy 40, 137–152 (1971)
Nadel, E.: Splenomegaly with excess numbers of Kurloff cells in guinea pigs treated with stilbestrol. J. Nat. Cancer Inst. 13, 605–617 (1952)
Revell, P., Dean, M., Vernon-Roberts, B., Muir, H., Marshall, A.: Inhibition of macrophage migration by a proteoglycan extracted by Kurloff cells of the guinea pig. Int. Arch. Allergy 43, 813–825 (1972)
Sen, S., Tribedi, B.: A critical study of the Kurloff body in guinea pigs. Ind. J. Med. Res. 43, 201–215 (1955)
Smith, E.: Certain characteristics of the leukocytes of guinea pig blood with particular reference to the Kurloff body. Blood, Spec. Issue 1, 125–141 (1947)
Welsh, R.: Kurloff body formation in the guinea pig lymphocytes. J. Ultrastruct. Res. 14, 556–570 (1966)
Woodcock, H.: An introduction to the study of hematophagy. J. Roy. Army Med. Corps. 37, 321–341, 418–431 (1921)
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Berendsen, P.B. Phagocytic inability of Kurloff cells in the lung and spleen of the guinea pig. Cell Tissue Res. 204, 513–517 (1979). https://doi.org/10.1007/BF00233661
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DOI: https://doi.org/10.1007/BF00233661