Abstract
Transitional nephrology seriously affects the manner in which radiological investigations and other forms of imaging are undertaken in the neonate. When this is complicated by acute renal failure then caution must be exerted in taking care of the neonate. The use of ultrasound and micturating cystourethrography are well described and form the baseline for all imaging of the renal tract. The physiological handling of TC99m DTPA and the contrasts used for IVU are described as well as the normal appearances of these techniques in the neonate. TC99m DMSA is also included, as are other modalities of imaging.
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Spitzer A (1978) Renal physiology and functional development. In: Edelman CM (ed) Pediatric kidney disease. Little, Brown and Company, Boston, pp. 25–128
Tanner JM (1949) Fallacy of per weight and per surface area standards and their relation to spurious correlation. J Appl Physiol 2: 1–15
Coulthard MG, Hey EN (1984) Weight as the best standard for glomerular filtration in the newborn. Arch Dis Child 59: 373–375
McCance RA, Widdowson EM (1952) The correct physiological basis on which to compare infant and adult renal function. Lancet II: 860–862
Friis-Hansen B (1961) Body water compartments in children: changes during growth and related changes in body composition. Pediatrics 28: 169–181
Gruskin AM, Edelmann CM, Yuan S (1970) Maturational changes in renal blood flow in piglets. Pediatr Res 4: 7–13
Olbing H, Blaufox MD, Aschinberg LC, Bernstein J, Spitzer A, Edelmann CM (1973) Postnatal changes in renal glomerular blood flow distribution in puppies. J Clin Invest 52: 2885–2895
Rodriguez-Soriano J, Vallo A, Castillo G, Oliveros R (1981) Renal handling of water and sodium in infancy and childhood: a study using clearance methods during hypotonic saline diuresis. Kidney Int 20: 700–704
Dillon MJ, Ryness JM (1975) Plasma renin activity and aldosterone concentration in children. Br Med J 4: 316–319
Aperia A, Broberger O, Herin P, Zetterström R(1979) Sodium excretion in relation to sodium intake and aldosterone excretion in newborn pretern and full term infants. Acta Paediatr Scand 68: 813–817
Al-Dahhan J, Haycock GB, Chantler C, Stimmler L (1983) Sodium homeostasis in term and preterm neonates. 1. Renal aspects. Arch Dis Child 58: 335–342
Dean RFA, McCance RA (1949) The renal response of infants and adults to the administration of hypertonic solutions of sodium chloride and urea. J Physiol 109: 81–97
Edelmann CM, Barnett HL, Troupkou V (1960) Renal concentrating mechanisms in newborn infants. Effect of dietary protein and water content, role of urea, and responsiveness to antidiuretic hormone. J Clin Invest 39: 1062–1069
Britton KE, Brown NSG (1971) Clinical renography. Lloyd-Luke, London
Hilson AJW, Maisey MN, Brown CB, Ogg CS, Bewick MS (1978) Dynamic renal transplant imaging with Tc-99m DTPA (Sn) supplemented by a transplant perfusion index in the management of renal tranplants. J Nucl Med 19: 994–1000
Chantler C, Garnett ES, Parsons V, Veall N (1969) Glomerular filtration rate measurement in man by the single injection method using51Cr-EDTA. Clin Sci 37: 169–180
O'Connor JF, Neuhauser EBD (1963) Total body opacification on conventional and high dose intravenous uropgraphy in infancy. Am J Roentgenol 90: 63–69
Piepsz A, Denis R, Ham HR, Dobbeleir A, Schulman C, Erbsmann F (1978) A simple method for measuring separate glomerular filtration rate using a single injection of99mTc-DTPA and the scintillation camera. J Pediatr 93: 769–774
Vivian G, Gordon I (1983) Comparison between individual kidney GFR estimation at 20 minutes with99mTc-DTPA and51Cr-EDTA GFR in children with a single kidney. Nucl Med Commun 4: 108–117
Diffey BL, Hall FM, Corfield JR (1976) The99mTc-DTPA dynamic renal scan with deconvolution analysis. J Nucl Med 17: 352–355
Britton KE, Whitfield HN, Nimmon CC, Hendry WF, Wickham JEA (1979) Obstructive nephrophathy: successful evaluation with radionuclides. Lancet I: 905–907
Vivian GC, Barratt TM, Todd-Pokropek A, Gordon I (1984) Renal parenchymal determination and analysis during dynamic99m-DTPA scans in children. Nucl Med Commun 5: 35–40
Levinsky NG, Levy M (1973) Clearance techniques.In: Orloff J, Berliner RW (eds) Handbook of physiology, vol 8: renal physiology. American Physiological Society, Washington, pp 103–118
Fetterman GF, Shuplock NA, Philipp FG, Gregg HS (1965). The growth and maturation of human glomeruli and proximal convolutions from term to adulthood. Studies by microdissection. Pediatrics 35: 601–699
McCance RA, Naylor NJB, Widdowson EM(1954) The response ov infants to a large dose of water. Arch Dis Child 29: 104–109
Suki W, Eknoyan G, Rector FC, Seldin DW (1966) Patterns of nephron perfusion in acute and chronic hydronephrosis. J Clin Invest 45: 122–131
Barratt TM, Chantler C (1970) Obstructive uropathy in infants. Proc R Soc Med 63: 1248–1250
Gosling JA, Dixon JS (1982) The structure of the normal and hydronephrotic upper urinary tract. In: O'Reilly PH, Gosling JA (eds) Idiopathic hydronephrosis. Springer, Berlin Heidelberg New York, pp 9–13
Gordon I (1985) Use of ultrasound and nuclear medicine techniques in paediatric urology. In: Whitaker RH, Woodard JR (eds) Paediatric urology. Butterworths, London, pp 34–42
Vivian G, Barratt TM, Todd-Pokropek A, Gordon I (1985) Physiological cariations of the normal transit time in children. Eur J Nucl Med 11: 179–181
Piepsz A, Ham HR, Erbsmann F, Hall M, Diffey BL, Goggin M, Hall FM, Lumbroso J, di Paola R, Bazin JP, di Paola M, Fries D (1982) A co-operative study on the clinical value of dynamic renal scanning with deconvolutional analysis. Br J Radiol 55: 419–433
O'Reilly PH, Testa HJ, Lawson RS, Farrar DJ, Edwards EC (1978) Diuresis renography in equivocal urinary tract obstruction. Br J Urol 50: 76–80
Sulyok E, Varga F, Nemeth M, Tenyi I, Csaba IF,Ertl T, Györy E (1980) Furosemide-induced alterations in electrolyte status, the function of renin-angiotensin-aldosterone system, and the urinary excretion of prostaglandins in the newborn infant. Pediatr Res 14: 765–768
Gruskin AB, Oetliker OH, Wolfish NM, Gootman NL, Bernstein J, Edelmann CM (1970) Effects of angiography on renal function in infants and piglets. J Pediatr 76: 41–53
Grainger RG (1982) Intravascular contrast media, the past, the present and the future. Br J Radiol 55: 1–18
Grainger RG (1986) The optimal concentration of contrast medium for aortography: a comparison of Hexabrix 320 and Hexabrix 250. Clin Radiol 37: 281–284
Steiner RM, Grainger RG, Memon N, Weiss D, Kanofsky PB, Menduke H (1980) The effect of contrast media of low osmolality on the peripheral arterial blood flow in the dog. Clin Radiol 31: 621–627
Cumberland DC (1981) Metrizamide in paediatric angiography. Ann Radiol 24: 99–104
Dawson P, Howell M (1986) The non-ionic dimers: a new class of contrast agents. Br J Radiol 59: 987–991
Gordon I (1986) Radiology and imaging of the urinary tract. In: Postlethwaite R (ed) Clinical paediatric nephrology. Wright, Bristol, pp 431–464
Hine AL, Lui E, Dawson P (1985) Contrast agent osmolality and plasma volume changes. Acta Radiol [Diag] (Stockh) 26: 753–756
Webster EW, Alpert NM, Brownall GL (1974) Radiation doses in pediatric nuclear medicine and diagnostic procedures. In: Jones AE, Wagner HN, Cooke RE (eds) Pediatric nuclear medicine. Saunders, Toronto, pp 47–52
Bingham JB, Maisey MN (1979) An evaluation of the use of99mTc-dimercaptosuccinic acid (DMSA) as a static renal imaging agent. Br J Radiol 51: 599–607
Goldraich NP, Alvarenga AR, Goldraich IH, Ramos OL, Sigulem D (1985) Renal accumulation of99mTc-DMSA in the artificially perfused isolated rat kidney. J Urol 76: 1282–1286
Goldraich NP, Goldraich IH (1982) Reflux nephropathy. Assessment using DMSA uptake. Int J Pediatr Nephrol 3: 120
van Luijk WHL, Ensing GJ, Meijer S, Donker AJM, Piers DA (1984) Is the relative99mTc-DMSA clearance a useful marker of proximal tubular dysfunction? Eur J Nucl Med 9: 439–442
Siddiqui A (1985) Radiation doses for various radiotracers. In: Siddiqui A (ed) Nuclear imaging in pediatrics. Year Book Medical Publishers, Chicago, pp 3–17
Currarino G (1985) Normal findings and anatomical variants. In: Silverman FN (ed) Caffey's pediatric x-ray diagnosis, 7th edn. Year Book Medical Publishers, Chicago, pp 1610–1614
Rosenbaum DM, Korngold E, Teale RL (1964) Sonographic assessment of renal length in normal children. Am J Radiol 142: 467–469
Erwin BC, Caroll BA, Muller H (1985) A sonographic assessment of neonatal parameters. J Ultrasound Med 4: 217–220
Blane CE, Bookstein FL, DiPietro MA, Kelsch RC (1985) Sonographic standards for normal infant kidney length. Am J Radiol 145: 1289–1291
Berdon WE (1985) Ultrasound in the neonate. In: Silverman FN (ed) Caffey's pediatric x-ray diagnosis, 7th edn. Year Book Medical Publishers,Chicago, pp 1890–1892
Atkinson GO, Kodroff MB, Gay BB, Ricketts RR (1985) Adrenal abscess in the neonate. Radiology 157: 221–224
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Gordon, I., Barratt, T.M. Imaging the kidneys and urinary tract in the neonate with acute renal failure. Pediatr Nephrol 1, 321–329 (1987). https://doi.org/10.1007/BF00849231
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DOI: https://doi.org/10.1007/BF00849231