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Glucose tolerance test in the Ainu

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Abstract

In an attempt to find out specific characteristics in carbohydrate metabolism in the Ainu, if any, glucose tolerance test was carried out. Between the Ainu and non-Ainu Japanese no differences were observed in the blood glucose, immunoreactive insulin and human growth hormone levels in the plasma after glucose load. Fasting levels of plasma FFA were significantly lower in the Ainu than in the Japanese. Changes in the FFA after glucose load were less in the Ainu, while the Japanese showed a marked rebound of the plasma FFA.

Zusammenfassung

Der Glukosetoleranztest wurde bei 10 Ainu und 20 Japanern (Studenten) durchgeführt. Signifikante Unterschiede im Blutzucker, immunreaktiven Insulin und humanen Wachstumshormon im Plasma wurden nach der Glukosegabe nicht gefunden. Die Nüchternwerte der freien Fettsäuren waren in den Ainu signifikant tiefer als bei den Japanern. Die Aenderungen der freien Fettsäuren nach Glukose waren bei den Ainu geringer, während die Japaner einen ausgeprägten "rebound effect" aufwiesen.

Resume

On a appliqué un test de tolérance à la glucose à 10 Aïnous et à 20 Japonais d'autres races (tous étudiants). On n'a pas décelé de différence significative après administration de glucose ni dans la teneur en sucre du sang, ni dans le taux d'insuline immunoréactive, ni dans les hormones humaines de croissance contenues dans le plasma. Les coefficients d'acides gras libres (FFA), après un jeûne ont été plus bas chez les Aïnous que chez les Japonais et cela de façon significative. La modification des acides gras libres après administration de glucose a été moins marquée chez les Aïnous alors que les Japonais présentaient un net "effet de rebondissement".

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Kuroshima, A., Itoh, S., Azuma, T. et al. Glucose tolerance test in the Ainu. Int J Biometeorol 16, 193–197 (1972). https://doi.org/10.1007/BF01810290

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  • DOI: https://doi.org/10.1007/BF01810290

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