Skip to main content
SpringerLink
Log in

Amikacin-containing regimens for treatment of nocardiosis in immunocompromized patients

  • Notes
  • Published:
European Journal of Clinical Microbiology Aims and scope Submit manuscript

Abstract

Eight patients with disseminated infections due to multi-resistant Nocardia asteroides were administered amikacin in combination with other effective antibiotics for a duration of 2 to 12 months. Seven patients were considered cured at follow-up after two years.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Palmer, D. L., Harvey, R. L., Wheeler, J. K.: Diagnostic and therapeutic considerations inNocardia asteroides infection. Medicine 1974, 5: 391–401.

    Google Scholar 

  2. Simpson, G. L., Stinson, E. B., Egger, M. J., Remington, J. S.: Nocardial infections in the immunocompromized host: a detailed study in a defined population. Reviews of Infectious Diseases 1981, 3: 492–507.

    PubMed  Google Scholar 

  3. Geiseler, P. J., Andersen, B. R.: Results of therapy in systemic nocardiosis. American Journal of the Medical Sciences 1979, 278: 188–194.

    PubMed  Google Scholar 

  4. Smego, R. A., Moeller, M. B., Gallis, H. A.: Trimethoprim-sulfamethoxazole therapy for nocardia infections. Archives of Internal Medicine 1983, 143: 711–718.

    PubMed  Google Scholar 

  5. Dalovisio, J. R., Pankey, G. A.: In vitro susceptibility ofNocardia asteroides to amikacin. Antimicrobial Agents and Chemotherapy 1978, 13: 128–129.

    PubMed  Google Scholar 

  6. Gutmann, L., Goldstein, F. W., Kitzis, M.-D., Hautefort, B., Darmon, C., Acar, J. F.: Susceptibility ofNocardia asteroides to 46 antibiotics including 22 beta-lactams. Antimicrobial Agents and Chemotherapy 1983, 2: 248–251.

    Google Scholar 

  7. Kitzis, M.-D., Gutmann, L., Acar, J. F.: In vitro susceptibility ofNocardia asteroides, to 21 beta-lactam antibiotics, in combination with three beta-lactamase inhibitors, and its relationship to the beta-lactamase content. Journal of Antimicrobial Chemotherapy 1985, 15: 23–30.

    PubMed  Google Scholar 

  8. Gombert, M. E.: Susceptibility ofNocardia asteroides to various antibiotics including newer beta-lactams trimethoprim-sulfamethoxazole, amikacin and N-formimidoyl thienamycin. Antimicrobial Agents and Chemotherapy 1982, 21: 1011–1012.

    PubMed  Google Scholar 

  9. Yogev, R., Greenslade, P., Firlit, C. F., Lewy, P.: Successful treatment ofNocardia asteroides infection with amikacin. Journal of Pediatrics 1980, 96: 771–773.

    PubMed  Google Scholar 

  10. Zaegel, R., Gaudouen, Y., Goldstein, F. W., Deloux, G., Blamoutier, J.: Nouvelle association thérapeutique utilisée avec succès dans un cas de nocardiose. La Presse Médicale 1983, 12: 643–644.

    Google Scholar 

  11. Meier, B., Metzger, U., Muller, F., Siegenthaler, W., Lüthy, R.: Successful treatment of a pancreaticNocardia asteroides abscess with amikacin and surgical drainage. Antimicrobial Agents and Chemotherapy 1986, 29: 150–151.

    PubMed  Google Scholar 

  12. Byrne, E., Brophy, B. P., Perrett, L. V.: Nocardia cerebral abscess: new concepts in diagnosis, management, and prognosis. Journal of Neurology, Neurosurgery and Psychiatry 1979, 42: 1038–1045.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Microbiologie Médicale, HÔpital Saint-Joseph, 7 rue Pierre Larousse, 75674, Paris Cedex 14, France

    F. W. Goldstein & J. F. Acar

  2. Laboratoire de Microbiologie Médicale, HÔpital Joseph Imbert, 18 rue du Pt. Wilson, 13200, Arles, France

    B. Hautefort

Authors
  1. F. W. Goldstein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. Hautefort
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. F. Acar
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goldstein, F.W., Hautefort, B. & Acar, J.F. Amikacin-containing regimens for treatment of nocardiosis in immunocompromized patients. Eur. J, Clin. Microbiol. 6, 198–200 (1987). https://doi.org/10.1007/BF02018213

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02018213

Keywords

Search

Navigation