Abstract
The authors describe two cases of solitary cerebral metastasis from non-seminatous germ cell tumors of the testis: in the first case, the histology was teratocarcinoma; in the second, it was embryonal carcinoma. Both patients underwent surgery, whole-brain radiotherapy and chemotherapy, and are still alive and disease-free after respectively 42 and 72 months. Although systemic metastasis from tumors of the testis are relatively common, they rarely involve the nervous system. A review of our cases and those reported in the literature shows that the outcome in these patients can be improved by the combined surgical, radiological and chemotherapeutic treatment of the metastasis.
Sommario
Gli autori riportano 2 casi di metastasi cerebrali solitarie da tumore non-seminoma del testicolo. Nel primo caso il tumore era istologicamente un teratocarcinoma, nel secondo un carcinoma embrionale. Entrambi i pazienti sono stati sottoposti a chirurgia, radioterapia e chemioterapia. La sopravvivenza è stata di 42 e 72 mesi rispettivamente. Sebbene le metastasi sistemiche da tumore del testicolo siano relativamente frequenti, raramente interessano il sistema nervoso. Dall'analisi dei nostri casi e di quelli riportati in letteratura, è risultato che la sopravvivenza dei pazienti può essere migliorata da un trattamento combinato delle metastasi, comprendente la chirurgia, la radioterapia e la chemioterapia.
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Salvati, M., Cervoni, L., Vitale, A.M. et al. Solitary cerebral metastasis from tumor of the testis: some observations about treatment in two cases. Ital J Neuro Sci 18, 173–175 (1997). https://doi.org/10.1007/BF02048487
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DOI: https://doi.org/10.1007/BF02048487