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Neuroendocrinological study of opioid and serotoninergic systems in migraine patients

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Abstract

PRL response to morphine in a group of migraine subjects was studied in the baseline condition and after neuroendocrinological inhibition and stimulation tests. No significant differences were found in comparison with control subjects. This demonstrated the integrity of the opioid system and serotoninergic pathways in migraine subjects.

Sommario

In un gruppo di soggetti emicranici è stata studiata la risposta in prolattina alla morfina in condizioni basali e con tests neuroendocrinologici di stimolazione ed inibizione.

Non si sono riscontrate significative differenze nei confronti dei soggetti di controllo.

Si è cosi documentata l'integrità del sistema degli oppiati endogeni e della via serotoninergica nei pazienti emicranici.

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Authors and Affiliations

  1. Centro Cefalee Istituto Neurologico “C. Besta”, Milano

    Bussone G., Boiardi A., Mantia L. La, Frediani F., Martini A., Giulio A. M. Di & Panerai A. E.

  2. Istituto di farmacologia, Scuola di medicina, Università, Milano

    Martini A., Giulio A. M. Di & Panerai A. E.

Authors
  1. Bussone G.
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  2. Boiardi A.
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  3. Mantia L. La
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  4. Frediani F.
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  5. Martini A.
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  6. Giulio A. M. Di
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  7. Panerai A. E.
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Bussone, G., Boiardi, A., La Mantia, L. et al. Neuroendocrinological study of opioid and serotoninergic systems in migraine patients. Ital J Neuro Sci 5, 413–416 (1984). https://doi.org/10.1007/BF02042625

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  • DOI: https://doi.org/10.1007/BF02042625

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