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Effects of daily soman administration on rabbit blood pressure, temperature, body weight, and erythrocyte and plasma cholinesterases

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References

  • Brezenoff HE, Giuliano R (1982) Cardiovascular control by cholinergic mechanism in the central nervous system. Ann Rev Pharmacol Toxicol 22:341–381

    Google Scholar 

  • Brezenoff HE, McGee J, Knight V (1984) The hypertensive response to soman and its relation to brain acetylcholinesterase inhibition. Acta Pharmacol et Toxicol 55:270–277

    Google Scholar 

  • Buccafusco JJ, Brezenoff HE (1979) Pharmacological study of a cholinergic mechanism within the rat posterior hypothalamic nucleus which mediates a hypertensive response. Brain Res 165:295–310

    PubMed  Google Scholar 

  • Daly M de Burgh, Wright PG (1956) The effects of anticholinesterases upon peripheral vascular resistance in the dog. J Physiol 133:475–497

    PubMed  Google Scholar 

  • Edery H, Berman HA (1985) Yohimbine antagonism of the vasodepression elicited by organophosphates applied on ventral medulla oblongata. J Autonom Nerv Sys/4:229–238

    Google Scholar 

  • Fowler PR, McKenzie JM (1967) Symposium: Automation in analytical chemistry. Mediad Inc, New York, pp 155–159

    Google Scholar 

  • Fukuyama GS, Stewart WC (1961) The effect of intravenous sarin on systemic blood pressure and peripheral vasomotor tone. Arch int Pharmacodyn 130:9–17

    PubMed  Google Scholar 

  • Grant RT, Rothschild P (1934) A device for estimating blood pressure in the rabbit. J Physiol 81:265–269

    Google Scholar 

  • Holmstedt B (1951) Synthesis and pharmacology of dimethylamido ethoxy-phosphoryl cyanide (tabun) together with a description of some allied anticholinesterase compounds containing the N-P bond. Acta Physiol Scand 25(Suppl) 90:1–120

    Google Scholar 

  • Hoskins B, Fernando JCR, Dulaney DK, Lim DK, Liu DD, Watanabe HK, Ho IK (1987) Tolerance to soman, sarin and tabun. Fed Proc 46:3162

    Google Scholar 

  • Hu CY, Robinson CP (1987) Effects of soman on norepinephrine content, release and metabolism and cholinesterase activity in rabbit blood vessels. Sixth Annual Bioscience Review 499–502

  • Levine JB, Scheldt RA, Nelson VA (1965) An automated micro determination of serum cholinesterase. Technicon Symposium, Automation in Analytical Chemistry, New York, NY

  • Philippu A (1981) Involvement of cholinergic systems of brain in central regulation of cardiovascular functions. J Autonom Pharmacol 1:321–330

    Google Scholar 

  • Preston E, Heath G (1972a) Atropine-insensitive vasodilatation and hypotension in the organophosphate-poisoned rabbit. Arch Int Pharmacodyn 200:231–244

    PubMed  Google Scholar 

  • Preston E, Heath C (1972b) Depression of the vasomotor system in rabbits poisoned with an organophosphate anticholinesterase. Acta Pharmacol et Toxicol 200:245–254

    Google Scholar 

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Hu, C.Y., Hung, C.Y. & Robinson, C.P. Effects of daily soman administration on rabbit blood pressure, temperature, body weight, and erythrocyte and plasma cholinesterases. Bull. Environ. Contam. Toxicol. 40, 365–372 (1988). https://doi.org/10.1007/BF01689093

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