Skip to main content
SpringerLink
Log in

Stereoselective crystallization induced by traces of dissolved optically active impurities

  • Published:
Journal of Molecular Evolution Aims and scope Submit manuscript

Summary

Isothermal crystallization of D,L-sodium-ammonium tartrate with traces of different impurities admixed shows that the added chiral contaminations produce a preferential crystallization of the tartrate isomer of same handedness. The critical lowest concentration of effective seeding agents is 0.1-0.5 %. 1 % optically active excess material induces 1.0-3.6 % optical purity in the deposited crystals. An analysis of the relevant data reported so far gives similar figures in different crystallization systems. The relation of the results to the suggested lattice energy difference between enantiomers is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bernal, J.D. (1967). The origin of life. London: Weidenfeld and Nicolson

    Google Scholar 

  • Bonner, W.A. (1972). Origins of molecular chirality. In: Exobiology, C. Ponnamperuma, ed., pp. 120–234. Amsterdam-London: North-Holland

    Google Scholar 

  • Harada, K. (1970). Naturwissenschaften57, 114

    Google Scholar 

  • Harada, K. (1972a). Bull Chem. Soc. Japan.45, 2859

    Google Scholar 

  • Harada, K. (1972b) Chem. Letters. 1057

  • Harrison, L.G. (1974). J. Mol. Evol.4, 99

    Google Scholar 

  • Kipping, F.S., Pope, W.J. (1898). J. Chem. Soc.73, 606

    Google Scholar 

  • Kovács, K.L., Garay, A.S. (1975). Nature254, 538

    Google Scholar 

  • Kovács, K.L. (1977). Proc. 2nd ISSOL Mecting, Kyoto, Japan

  • McKenzie, A. (1915). J. Chem. Soc.107, 440

    Google Scholar 

  • Northrop, J.H. (1957). Proc. Nat. Acad. Sci. U.S.43, 304

    Google Scholar 

  • Ostromisslenskii, I. (1908). Ber.41, 3035

    Google Scholar 

  • Pincock, R.E., Branshaw, R.P., Perkins, R.R. (1974). J. Mol. Evol.4, 67

    Google Scholar 

  • Secor, R.M. (1963). Chem. Rev.63, 297

    Google Scholar 

  • Thiemann, W. (1974a). Naturwissenschaften61, 476

    Google Scholar 

  • Theimann, W. (1974b). J. Mol. Evol.4, 85

    Google Scholar 

  • Thiemann, W., Darge, W. (1974). Origins of Life5, 263

    Google Scholar 

  • Thiemann, W., Wagener, K. (1970). Angew. Chem.82, 776

    Google Scholar 

  • Wald, G. (1957). Ann. N.Y. Acad. Sci.69, 369

    Google Scholar 

  • Yamagata, Y. (1966). J. Theoret. Biol.11, 495

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Biophysics, Biological Research Center, Hungarian Academy of Sciences, P.O. Box 521, H-6701, Szeged, Hungary

    K. L. Kovács

Authors
  1. K. L. Kovács
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kovács, K.L. Stereoselective crystallization induced by traces of dissolved optically active impurities. J Mol Evol 10, 161–166 (1977). https://doi.org/10.1007/BF01751809

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01751809

Key words

Search

Navigation