Abstract
The chromatid-type and labile chromosome-type aberrations occurred frequently in the factory-employees control group, probably caused by airborne pollution. Workers producing TECB (1,2,4,5-tetrachlorobenzene) showed a cluster of chromosome aberrations. No appreciable increase was found in the lindane workers; chromatid-type aberrations were moderately increased in workers in the Basudin E and the Safidon 40 WP groups; stable chromosome-type aberrations were observed in the Ditrifon 50 and the Basudin E groups.
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Buckton, K. E., P. A. Jacobs, W. M. Court-Brown and R. Doll: A study of chromosome damage persisting after x-ray therapy for ankylosing spondylitis. Lancetii, 676 (1962).
Buckton, K. E., and H. J.Evans: Methods for the analysis of human chromosome aberrations. WHO (1973).
Court-Brown, W. M.: Human population cytogenetics. Amsterdam: North-Holland Publ. Co. (1967).
Czeizel, A., Trinh van Bao, I. Szabo, and P. Ruzicska: Human chromosome aberrations in acute organic phosphorus acid ester (pesticide) intoxication. Mutat. Res.21, 187 (1973).
Czeizel, A., M. Osztovics, and J. Király: Studies on chromosome mutagenicity of organophosphate insecticides in workers. Firenze: Vth Annual Meeting of the EEMS (1975).
Czeizel, A., and J. Király: Chromosome examinations in workers producing Klorinol® and Buvinol®. In L. Bánki (ed.): The development of a pesticide as a complex scientific task. Budapest: Medicina Press (1976).
Dean, A. C. R., and H. S. Law: The action of 2,4-dichlorophenoxyacetic acid on Aerobacter aerogenes. Ann. Bot. (London)28, 703 (1964).
Gebhardt, E.: The treatment of human chromosomesin vitro: Results. In F. Vogel and G. Röhrborn (ed.): Chemical mutagenesis in mammals and man. Berlin-Heidelberg-New-York: Springer-Verlag (1970).
Kiárly, J., I. Szentesi, M. Ruzicska, and A. Czeizel: Chromosome examinations on workers producing organic phosphate insecticides. Munkavédelem22, 27 (1976) (Hungarian).
Kostoff, D.: Cytogenetic changes and atypical growth induced by hexachlorocyclohexane. Current Science17, 294 (1948).
Markarian, D. S.: Cytogenetic effect of some chlorine containing organic insecticides on mouse bone marrow cell nuclei. Genetika1, 132 (1966).
Moorhead, P. S., P. C. Nowell, W. J. Mellman, D. M. Battips, and D. A. Hungerford: Chromosome preparations of leucocytes cultured from human peripheral blood. Exp. Cell. Res.20, 613 (1960).
Pilinskaya, M. A.: Chromosome aberrations in the persons contacted with Ziram. Genetika6, 157 (1970).
Pollini, G., and R. Colombi: Il danno cromosomico dei limfociti rellémspatia benzenica. Med. Lavoro.55, 641 (1964).
Tough, I. M., and W. M. Court-Brown: Chromosome aberrations and exposure to ambient benzene. Lanceti. 684 (1965).
Trinh van Bao, and I. Szabó: Chromosome damage in acute organic phosphate insecticide intoxications. Orv. Hetil.113, 2593 (1972) (Hungarian).
Trinh van Bao, I. Szabó, P. Ruzicska and A. Czeizel: Chromosome aberrations in patients suffering acute organic phosphate insecticide intoxication. Humangenetik24, 33 (1974)a.
: Chromosome damage in acute organic phosphate insecticide intoxications. Egészségtudomany18, 348 (1974)b (Hungarian).
Yoder, J., M. Watson, and W. W. Benson: Lymphocyte chromosome analysis of agricultural workers during extensive occupational exposure to pesticides. Mutat. Res.21, 335 (1973).
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Király, J., Szentesi, I., Ruzicska, M. et al. Chromosome studies in workers producing organophosphate insecticides. Arch. Environ. Contam. Toxicol. 8, 309–319 (1979). https://doi.org/10.1007/BF01056247
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DOI: https://doi.org/10.1007/BF01056247