Summary
Base-catalyzed cyclization of ethoxymethylenemalononitrile2 with substituted acetoacetates1 a–c leads to the ethyl benzoates3 a–c. Depending on the reaction conditions either ethyl 4-aminobenzoates3 d–i or ethyl 4-(2,2-dicyanethylene)aminobenzoates4 d–h are available from2 and the 4-oxyacetoacetates1 d–i. The preparation of the acetoacetates1 a–c and1 g–i is also described.
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Schmidt, HW. Cyclisierungsreaktionen von Ethoxymethylenmalononitril mit 4-substituierten Acetessigestern. Monatsh Chem 120, 891–897 (1989). https://doi.org/10.1007/BF00811128
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DOI: https://doi.org/10.1007/BF00811128