Skip to main content
SpringerLink
Log in

One pot synthesis of the dinucleoside phosphonate GpCH2U

Eintopfsynthese des Dinucleosidphosphonats GpCH2U

  • Organische Chemie Und Biochemie
  • Published:
Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary

The preparation of the dinucleoside phosphonate GpCH2U, starting from the isosteric phosphonate analogue of uridine (3) and the guanosine derivative5 is described.

Zusammenfassung

Die Herstellung des Dinucleosidphosphonats GpCH2U aus dem isosteren Phosphonatanalogen von Uridin (3) und dem Guanosinderivat5 wird beschrieben.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Jones GH, Albrcht HP, Damodaran NP, Moffatt JG (1970) J Am Chem Soc92: 5510–5511

    Google Scholar 

  2. Jones GH, Moffatt JG (1968) Am Chem Soc90: 5337–5338

    Google Scholar 

  3. Albrecht HP, Jones GH, Moffatt JG (1984) Tetrahedron40: 79–85

    Google Scholar 

  4. This compound was synthesised by the method ofMoffat [2], but using the lithium salt of tetraethyl methylenediphosphonate instead of diphenyltriphenylphosphoranylidenemethyl phosphonate

  5. Haikal A (in press)

  6. Zegers I, Haikal A, Palmer R, Wyns L (1994) J Biol Chem269: 127–133

    Google Scholar 

Download references

Author information

Author notes

  1. A. Haikal

    Present address: Faculity of Science, Department of Chemistry, Zagazig University, Zagazig, Egypt

Authors and Affiliations

  1. Institute voor Moleculaire Biologie, Vrije Universiteit Brussel, Brussels, Belgium

    A. Haikal, J. Doumen & L. Wyns

Authors
  1. A. Haikal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Doumen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. Wyns
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Haikal, A., Doumen, J. & Wyns, L. One pot synthesis of the dinucleoside phosphonate GpCH2U. Monatsh Chem 126, 1031–1033 (1995). https://doi.org/10.1007/BF00811023

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00811023

Keywords

Search

Navigation