Summary
Complete cerebral ischemia was produced in normothermic cats by clamping the innominate and subclavian arteries and simultaneous lowering of the systemic blood pressure. The effect of ischemia on the sensorimotor cortex was assessed by neurophysiological, electronmicroscopical, and biochemical observations. Nerve cell excitability, synaptic transmission and EEG activity recovered after ischemia of up to 1 hr. The neurophysiological recovery was paralleled by the restoration of the energy-producing metabolism which approached normal values when spontaneous EEG activity reappeared. Electronmicroscopy revealed the structural preservation of the cortex after the recovery of function.
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Hossmann, K.A., Sato, K. The effect of ischemia on sensorimotor cortex of cat. Z. Neurol. 198, 33–45 (1970). https://doi.org/10.1007/BF00316134
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DOI: https://doi.org/10.1007/BF00316134