Skip to main content
Log in

Stenosis and occlusion of the subclavian artery: ultrasonographic and clinical findings

  • Original Investigations
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Summary

Continuous-wave (CW) Doppler sonography has proved to be a reliable tool both to detect subclavian stenosis or occulusion and to detect reversal of blood flow in the vertebral artery. This method is entirely atraumatic and in contrast to angiography allows investigation of asymptomatic patients and provides more representative data for epidemiological studies. The incidence of subclavian stenosis or occlusion was 1.15% among the 23,500 patients examined in our department between 1978 and 1985. Of the 272 patients with unilateral or bilateral subclavian stenosis or occlusion, 54% were asymptomatic with no subjective complaints and were normal upon neurological examination; 29% reported vertebrobasilar transient ischaemic attacks (TIAs), with or without concomitant TIAs or infarction in the vascular territory of the carotid arteries; and 17% complained of symptoms exclusively referring to the region of carotid blood supply. Reversal of blood flow in the ipsilateral vertebral artery was detected in 152 patients (56%). The incidence of neurological symptoms within this group was double that found in patients without steal. None of the patients suffered from permanent vertebrobasilar damage. In most cases, subclavian artery disease was due to atherosclerosis. For 13 patients an inflammatory, iatrogenic, traumatic, or congenital aetiology could be assumed. The marked preponderance of left-sided subclavian stenosis or occlusion, reported by others, could be confirmed among our patients, but was less pronounced for tight stenoses than for occlusions. Mild-to-moderate subclavian stenoses were about equally distributed on each side.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ausman JI, Shrontz CE, Pearce JE, Diaz FG, Crecelius JL (1985) Vertebrobasilar insufficiency. A review. Arch Neurol 42:803–807

    Article  CAS  PubMed  Google Scholar 

  2. Baker RA, Rosenbaum AE, Robertson GH (1975) Segmental intervertebral anastomosis in subclavian steal. Br J Radiol 48:101–107

    Article  CAS  PubMed  Google Scholar 

  3. Bernsmeier A, Held K (1972) The aortic arch syndrome. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology. Vascular diseases of the nervous system. II. North-Holland, Amsterdam, pp 398–421

    Google Scholar 

  4. Borushok MJ, White RI, Oh KS, Dorst JP (1974) Congenital subclavian steal. Am J Roentgenol 121:559–564

    Article  CAS  Google Scholar 

  5. Bosniak MA (1963) A collateral pathway through the vertebral arteries associated with obstruction of the innominate ansd proximal subclavian arteries. Radiology 81:89–94

    Article  CAS  PubMed  Google Scholar 

  6. Büdingen HJ, von Reutern GM, Freund HJ (1982) Doppler-Sonographie der extrakraniellen Hirnarterien. Thieme, Stuttgart New York

    Google Scholar 

  7. Caplan LR, Rosenbaum AE (1975) Role of cerebral angiography in vertebrobasilar occlusive disease. J Neurol Neurosurg Psychiatry 38:601–612

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Carey P (1967) The vertebral steal. J Neurol Neurosurg Psychiatry 30:85

    Google Scholar 

  9. Conrad MC, Toole JF, Janeway R (1965) Hemodynamics of the upper extremities in subclavian steal syndrome. Circulation 32:346–351

    Article  CAS  PubMed  Google Scholar 

  10. Contorni L (1960) Il circolo collaterale vertebro-vertebrale nella obliterazione dell'arteria succlavia alla sua origine. Minerva Chir 15:268–271

    CAS  PubMed  Google Scholar 

  11. Diener HC, Dichgans J, Voigt K (1981) Functional anatomy of extracranial arteries in occlusive vascular disease by direct continuous-wave Doppler sonography. Cardiovasc Intervent Radiol 4:193–201

    Article  CAS  PubMed  Google Scholar 

  12. Fields WS (1970) Reflections on “the subclavian steal”. Stroke 1:320–324

    Article  CAS  PubMed  Google Scholar 

  13. Fields WS, Lemak NA (1972) Joint study of extracranial arterial occlusion. VII. Subclavian steal. A review of 168 cases. JAMA 222:1139–1143

    Article  CAS  PubMed  Google Scholar 

  14. Fisher CM (1961) A new vascular syndrome — “the subclavian steal”. N Engl J Med 265:912–913

    Article  Google Scholar 

  15. Freund HJ, Schoop W (1966) Neurologische Störungen bei angiographisch nachgewiesenem Subclavia-Vertebralis-Anzapfsyndrom (subclavian steal) vor und nach dosierter Armarbeit. Dtsch Z Nervenheilkd 189:136–152

    Article  CAS  PubMed  Google Scholar 

  16. Heidrich H, Bayer O (1969) Symptomatology of the subclavian steal syndrome. Angiology 20:406–413

    Article  CAS  PubMed  Google Scholar 

  17. Herrschaft H (1970) Die Zirkulationsstörungen der Arteria vertebralis. Arch Psychiatr Nervenkr 213:22–45

    Article  CAS  PubMed  Google Scholar 

  18. Janeway R, Conrad M, Toole JF (1965) Chronic reversal of vertebral artery flow. An experimental study in dogs. Neurology 15:430–437

    Article  CAS  PubMed  Google Scholar 

  19. Killen DA, Foster JH, Gobbel WG, Stephenson SE, Collins HA, Billings FT, Scott HW (1966) The subclavian steal syndrome. J Thorac Cardiovasc Surg 51:539–560

    CAS  PubMed  Google Scholar 

  20. Motarjeme A, Keifer JW, Zuska AJ, Nabawi P (1985) Percutaneous transluminal angioplasty for treatment of subclavian steal. Radiology 155:611–613

    Article  CAS  PubMed  Google Scholar 

  21. Müller N (1958) Das Aortenbogensyndrom (“pulseless disease”). Fortschr Neurol Psychiatr 26:637–654

    Google Scholar 

  22. North RR, Fields WS, DeBakey ME, Crawford ES (1962) Brachial-basilar insufficiency syndrome. Neurology 12:810–820

    Article  CAS  PubMed  Google Scholar 

  23. Patel A, Toole JF (1965) Subclavian steal syndrome — reversal of cephalic blood flow. Medicine (Baltimore) 44:289–303

    Article  CAS  PubMed  Google Scholar 

  24. Reivich M, Holling HE, Roberts B, Toole JF (1961) Reversal of blood flow through the vertebral artery and its effect on cerebral circulation. N Engl J Med 265:878–885

    Article  CAS  PubMed  Google Scholar 

  25. Reutern GM von, Pourcelot L (1978) Cardiac cycle-dependent alternating flow in vertebral arteries with subclavian artery stenoses. Stroke 9:229–236

    Article  Google Scholar 

  26. Reutern GM von, Büdingen HJ, Freund HJ (1976) Dopplersonographische Diagnostik von Stenosen und Verschlüssen der Vertebralarterien und des Subclavian-Steal-Syndroms. Arch Psychiatr Nervenkr 222:209–222

    Article  CAS  PubMed  Google Scholar 

  27. Ringelstein EB, Zeumer H (1984) Delayed reversal of vertebral blood flow following percutaneous transluminal angioplasty for subclavian steal syndrome. Neuroradiology 26:189–198

    Article  CAS  PubMed  Google Scholar 

  28. Sammartino WF, Toole Jf (1964) Reversed vertebral artery flow. The effect of limb exercise and hypertensive agents. Arch Neurol 10:590–594

    Article  CAS  PubMed  Google Scholar 

  29. Santschi DR, Frahm CJ, Pascale LR, Dumanian AV (1966) The subclavian steal syndrome. Clinical and angiographic considerations in 74 cases in adults. J Thorac Cardiovasc Surg 51:103–112

    CAS  PubMed  Google Scholar 

  30. Schmidt H, Heine H, Raskovic M (1967) Klinik und Prognose de Aortenbogen-Syndroms. Münch Med Wochenschr 14:777–783

    Google Scholar 

  31. Sharon M, Asinger RW, Hodges M (1981) Reactive hyperemia for the clinical diagnosis of subclavian steal syndrome: report of a case. Stroke 12:369–371

    Article  CAS  PubMed  Google Scholar 

  32. Siekert RG, Millikan CH, Whisnant JP (1964) Reversed blood flow in the vertebral arteries. Ann Intern Med 61:64–72

    Article  CAS  PubMed  Google Scholar 

  33. Simon M, Rabinov K, Horenstein S (1962) Proximal subclavian artery occlusion and reversed vertebral blood flow to the arm. Clin Radiol 13:201–206

    Article  CAS  PubMed  Google Scholar 

  34. Toole JF (1964) Reversed vertebral artery flow and cerebral vascular insufficiency. Ann Intern Med 61:159–162

    Article  CAS  PubMed  Google Scholar 

  35. Vollmar J, El Bayar M, Kolmar D, Pfleiderer T, Diezel PB (1965) Zerebrale Durchblutungsinsuffizienz bei Verschlußprozessen der Arteria subclavia (“subclavian steal effect”). Dtsch Med Wochenschr 90:8–14

    Article  CAS  PubMed  Google Scholar 

  36. Walker DW, Acker JD, Cole CA (1982) Subclavian steal syndrome detected with Duplex pulsed Doppler sonography. AJNR 3:615–618

    CAS  PubMed  Google Scholar 

  37. Wheeler HB (1967) Surgical treatment of subclavian-artery occlusions. N Engl J Med 276:711–717

    Article  CAS  PubMed  Google Scholar 

  38. Williams D, Wilson TG (1962) The diagnosis of the major and minor syndromes of basilar insufficiency. Brain 85:741–774

    Article  CAS  PubMed  Google Scholar 

  39. Williams SJ (1986) Chronic upper extremity ischemia: current concepts in management. Surg Clin North Am 66:355–375

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ackermann, H., Diener, H.C. & Dichgans, J. Stenosis and occlusion of the subclavian artery: ultrasonographic and clinical findings. J Neurol 234, 396–400 (1987). https://doi.org/10.1007/BF00314084

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00314084

Key words

Navigation