Summary
A 59-year-old man is reported, who became aphasic after left thalamic infarction, shown by CT. His speech was fluent, with reduced voice volume, impaired auditory and reading comprehension, verbal paraphasias but intact repetition skills. A single photon emission computed tomography (SPECT) scan to measure regional cerebral flow (rCBF) showed a reduction of flow in the parietotemporal areas of the left hemisphere. It is suggested that thalamic aphasia could result from structural subcortical damage with a homolateral functional cortical deficit leading to the specific aphasic disturbance.
References
Cappa SF, Vignolo LA (1979) “Transcortical” features of aphasia following left thalamic hemorrhage. Cortex 15:121–130
Celsis P, Goldman T, Henriksen L, Lassen NA (1981) A method for calculating regional cerebral blood flow from emission computed tomography of inert gas concentrations. J Comput Assist Tomogr 5:641–645
Darley FL, Brown J, Swenson WM (1975) Language changes after neurosurgery for parkinsonism. Brain Lang 2:65
Déjerine R, Roussy G (1906) Le syndrome thalamique. Rev Neurol (Paris) 14:521–536
Elghozi D, Strube E, Signoret JL, Cambier J, Lhermitte F (1978) Quasi-aphasie lors de lésion du thalamus. Relation du trouble du language et de l'activation élective de l'hémisphére gauche dans 4 observations de lésions thalamiques gauches et droites. Rev Neurol (Paris) 134:557–574
Gorelick PB, Hier DB, Benevento L, Levitt S, Tare M (1984) Aphasia after thalamic infarction. Arch Neurol 41:1296–1299
Hillemand P (1925) Contribution à l'étude des syndromes de la région thalamique. Thése, Jouve, Paris
Lassen NA, Henriksen I, Paulson O (1981) Regional cerebral blood flow in stroke by 133-Xenon inhalation and emission tomography. Stroke 12:284–288
Lhermitte F (1984) Language disorders and their relationship to thalamic lesion. In: Rose C (ed) Advances in neurology, vol 47. Raven, New York
Luria AR (1967) Le funzioni corticali superiori nell'uomo. Giunti, Firenze
Mazaux JM, Orgogozo JM (1982) Étude analytique et quantitative des troubles du language par lésion du thalamus gauche: l'aphasie thalamique. Cortex 18:403–416
Metter JE, Riege WH, Hansen WR, Phelps ME (1981) 18FDG positron computed tomography: a study of aphasia. Ann Neurol 10:173–183
Metter JE, Riege WH, Hanson WR, Kuhl D, Phelps ME, Squire LR, Wasterlain CG, Benson DF (1983) Comparison of metabolic rates, language and memory in subcortical aphasias. Brain Lang 19:33–47
Ojemann GA (1975) Language and the thalamus: object naming and recall during and after thalamic lesions in humans. Brain Lang 2:101–120
Puel M, Demonet JF, Cardebat D, Bonafé A, Gazounad Y, Guiraud-Chaumeil B, Rascol A (1984) Aphasie sous-corticales: étude neurolinguistique avec scanner X de 25 cas. Rev Neurol (Paris) 140:695–710
Walker AE (1938) The primate thalamus. University of Chicago Press, Chicago