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Determination of Transaminase Activity in Dogs' Serum and Lymph after Hepatic Damage due to Acute Biliary Obstruction

Abstract

IT is known that glutamic-oxaloacetic acid transaminase (GOT) and glutamic-pyruvic acid transaminase (GPT) are increased in sera of patients suffering from certain liver diseases1; but there are scarcely any data available about the pathways of these enzymes. We have therefore studied the changes of the concentration of transaminase of hepatic origin at various points of the blood and lymphatic circulation after damage to the liver caused experimentally by biliary obstruction.

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References

  1. Wroblewski, F., and LaDue, J. S., Ann. Int. Med., 43, 345 (1955).

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  2. Umbreit, W. W., Kingsley, G. R., Schaffert, R. R., and Siplet, H., J. Lab. and Clin. Med., 49, 454 (1957).

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BRAUN, P., PAPP, M. & HORVÁTH, I. Determination of Transaminase Activity in Dogs' Serum and Lymph after Hepatic Damage due to Acute Biliary Obstruction. Nature 183, 48–49 (1959). https://doi.org/10.1038/183048a0

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