Abstract
CALCIUM ions are critically involved in the cholinergic neuromuscular transmission process. Presynaptically, Ca2+ is required in transmitter release1 while postsynaptically, it plays a role in acetylcholine-receptor kinetics2. Furthermore, Ca2+ sets off a chain of physicochemical events which leads to muscle contraction3.
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DEVORE, D., NASTUK, W. Effects of ‘calcium ionophore’ X537A on frog skeletal muscle. Nature 253, 644–646 (1975). https://doi.org/10.1038/253644a0
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DOI: https://doi.org/10.1038/253644a0
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