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Factors controlling the Interconversion of Enzyme–Substrate Compounds of Pig Heart Lactate Dehydrogenase

Abstract

Stopped flow and temperature jump experiments make possible a description of the individual catalytic steps. Detailed results favour the induced fit hypothesis of enzyme action.

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CRIDDLE, R., McMURRAY, C. & GUTFREUND, H. Factors controlling the Interconversion of Enzyme–Substrate Compounds of Pig Heart Lactate Dehydrogenase. Nature 220, 1091–1095 (1968). https://doi.org/10.1038/2201091a0

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