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Today's SCID-hu mouse

Nature volume 348, pages 561–562 (1990)Cite this article

Use of the SCID-hu mouse — an immunodeficient mouse transplanted with relevant organs of the human immune system — as a preclinical testing system for human therapeutics is discussed.

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Author notes

  1. H. Kaneshima, C. Baum, B. Chen, R. Namikawa, H. Outzen, L. Rabin, A. Tsukamoto and J.M. McCune: The authors would like to acknowledge John Krowka, Jan Laman, Susan Mayo, Bruno Peault, Chu-Chih Shih and Phil Streeter at SyStemix, and living L Weissman at Stanford University for their useful suggestions. We thank the Transplantation and Animal production groups for their help in making these studies possible.

Authors and Affiliations

  1. SyStemix, Inc., 3400 West Bayshore Road, Palo Alto, California, 94303, USA

    H. Kaneshima, C. Baum, B. Chen, R. Namikawa, H. Outzen, L. Rabin, A. Tsukamoto & J. M. McCune

Authors
  1. H. Kaneshima
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  2. C. Baum
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  3. B. Chen
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  4. R. Namikawa
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  5. H. Outzen
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  6. L. Rabin
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  7. A. Tsukamoto
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  8. J. M. McCune
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Kaneshima, H., Baum, C., Chen, B. et al. Today's SCID-hu mouse. Nature 348, 561–562 (1990). https://doi.org/10.1038/348561a0

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