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Carcinogenic action of dimethylnitrosamine in trout not related to methylation of nucleic acids and protein in vivo

  • Specialia
  • Anatomica, Embryologica, Histologica, Carcinologica
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Zusammenfassung

Zur Klärung des Zusammenhanges zwischen carcinogener und alkylierender Wirkung von Dimethylnitrosamin wurde die Bildung von14C-7-Methylguanin in der Leber-RNA von Tauben, Fröschen und Forellen nach Gabe von14C-Dimethylnitrosamin untersucht. Dabei konnte14C-7-Methylguanin in der Leber-RNS von Tauben und Fröschen nachgewiesen werden, während RNA, DNS und Protein der Leber bei Forellen nicht markiert wurden.

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Authors and Affiliations

  1. Institut für experimentelle Toxikologie und Chemotherapie, Deutsches Krebsforschungszentrum, D-69, Heidelberg, Germany

    F. W. Krüger, G. Walker & M. Wiessler

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  1. F. W. Krüger
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  2. G. Walker
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  3. M. Wiessler
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Krüger, F.W., Walker, G. & Wiessler, M. Carcinogenic action of dimethylnitrosamine in trout not related to methylation of nucleic acids and protein in vivo. Experientia 26, 520–522 (1970). https://doi.org/10.1007/BF01898485

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  • DOI: https://doi.org/10.1007/BF01898485

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