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Depression of humoral and cell-mediated immune responses by coxsackieviruses in mice

  • Haematologica, Immunologica
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Summary

Adult mice infected with coxsackieviruses A-15, B-1, B-2, B-4 and B-6 showed depressed antibody responses to unrelated antigens; mice infected with coxsackievirus B-3 developed reduced humoral and cell-mediated immune responses. These findings might have clinical and epidemiological implications.

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Authors and Affiliations

  1. Institute of Microbiology and Institute of Hygiene, University of Pisa, I-56100, Pisa, Italy

    M. Bendinelli, A. Ruschi, A. Campa & A. Toniolo

Authors
  1. M. Bendinelli
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  2. A. Ruschi
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  3. A. Campa
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  4. A. Toniolo
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Additional information

We are very much indebted to C. M. Avio for statistical help.

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Bendinelli, M., Ruschi, A., Campa, A. et al. Depression of humoral and cell-mediated immune responses by coxsackieviruses in mice. Experientia 31, 1227–1229 (1975). https://doi.org/10.1007/BF02326807

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  • DOI: https://doi.org/10.1007/BF02326807

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