Skip to main content
Log in

Chemotaxis of rabbit macrophages in vitro: Inhibition by drugs

  • Specialia Pharmacologica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Chemotaxis of rabbit macrophages was inhibited in vitro by phenylbutazone and sodium salicylate, but not by other antiinflammatory agents. Other inhibitory compounds were colchicine, vincristine, PHA, Con A, iodoacetic acid, cytochalasin B, and EDTA. Some of these in vitro results contrast apparently with in vivo effects.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. J. F. Borel, Experientia29, 676 (1973).

    Article  CAS  PubMed  Google Scholar 

  2. S. Boyden, J. exp. Med.115, 453 (1962).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. J. F. Borel, Int. Arch. Allergy39, 247 (1970).

    Article  CAS  PubMed  Google Scholar 

  4. R. Snyderman, L. C. Altman, M. S. Hausman andS. E. Mergenhagen, J. Immunol.108, 857 (1972).

    Article  CAS  PubMed  Google Scholar 

  5. H. U. Keller, M. W. Hess andH. Cottier, inChemotaxis: Its Biology and Biochemistry (Ed.E. Sorkin; Karger, Basel 1974), vol. 19, p. 112.

    Google Scholar 

  6. H. U. Keller, J. F. Borel, P. C. Wilkinson, M. W. Hess andH. Cottier, J. immun. Methods1, 165 (1972).

    Article  CAS  Google Scholar 

  7. D. A. Boetcher andM. S. Meltzer, J. natn. Cancer Inst.54, 795 (1975).

    CAS  Google Scholar 

  8. M. E. Miller, inThe Phagocytic Cell in Host Resistance (Eds.J. A. Bellanti andD. H. Dayton; Raven Press, New York 1975), p. 295.

    Google Scholar 

  9. J. J. Rinehart, S. P. Balcerzak, A. L. Sagone, A. F. LoBuglio, J. clin. Invest.54, 1337 (1974).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. M. Rabinovitch andM. J. Destefano, Expl Cell Res.88, 153 (1974).

    Article  CAS  Google Scholar 

  11. K. Kumagai andS. Arai, J. reticul.-endothel. Soc.13, 507 (1973).

    CAS  Google Scholar 

  12. A. C. Allison, inChemotaxis: Its Biology and Biochemistry (Ed.E. Sorkin; Karger, Basel 1974), vol. 19, p. 191.

    Google Scholar 

  13. U. Bandmann, L. Rydgren andB. Norberg, Expl Cell Res88, 63 (1974).

    Article  CAS  Google Scholar 

  14. G. M. Edelman, I. Yahara andJ. L. Wang, Proc. natn. Acad. Sci., USA70, 1442 (1973).

    Article  CAS  Google Scholar 

  15. R. Snyderman andC. E. Stahl, inChemotaxis: Its Biology and Biochemistry (Ed.E. Sorkin; Karger, Basel 1974), vol. 19, p. 284.

    Google Scholar 

  16. R. C. Page, P. Davies andA. C. Allison, J. reticul.-endothel. Soc.15, 413 (1974).

    CAS  Google Scholar 

  17. R. J. North, J. exp. Med.134, 1485 (1971).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. M. Di Rosa, L. Sorrentino andL. Parente, J. Pharm. Pharmac.24, 575 (1972).

    Article  Google Scholar 

  19. C. Feurer andJ. F. Borel, inChemotaxis: Its Biology and Biochemistry (Ed.E. Sorkin; Karger, Basel 1974), vol. 19, 161.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Borel, J.F., Feurer, C. Chemotaxis of rabbit macrophages in vitro: Inhibition by drugs. Experientia 31, 1437–1439 (1975). https://doi.org/10.1007/BF01923232

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01923232

Keywords

Navigation