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Inhibition of DNA synthesis in concanavalin A stimulated rat lymph node cells by serum from arthritic rats

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Summary

Serum from adjuvant arthritic rats inhibits the mitogenic response of rat lymph node cells to concanavalin A, leaving unaffected the response to phytohemagglutinin. This activity is already evident 4 days after adjuvant administration and persists for at least 28 days.

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Authors and Affiliations

  1. Dept. of Pharmacology, Leo Pharmaceutical Products, 2750, Ballerup, Denmark

    L. Binderup, E. Bramm & E. Arrigoni-Martelli

Authors
  1. L. Binderup
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  2. E. Bramm
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  3. E. Arrigoni-Martelli
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Binderup, L., Bramm, E. & Arrigoni-Martelli, E. Inhibition of DNA synthesis in concanavalin A stimulated rat lymph node cells by serum from arthritic rats. Experientia 33, 390–391 (1977). https://doi.org/10.1007/BF02002844

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  • DOI: https://doi.org/10.1007/BF02002844

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