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Effect of sex hormones on plasma cholesterol in castrated and noncastrated male rats

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Summary

The administration of estradiol to both castrated and noncastrated male rats was associated with significantly increased plasma cholesterol levels as compared to controls, the estradiol in the noncastrated rats overriding the tendency of testosterone to lower plasma cholesterol.

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Authors and Affiliations

  1. Bockus Research Institute and Department of Physiology, University of Pennsylvania School of Medicine, 19146, Philadelphia, Pa., USA

    G. M. Fischer & M. L. Swain

Authors
  1. G. M. Fischer
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  2. M. L. Swain
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Acknowledgement. This work was supported by USPHS Grant NHLBI 17721.

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Fischer, G.M., Swain, M.L. Effect of sex hormones on plasma cholesterol in castrated and noncastrated male rats. Experientia 34, 624–625 (1978). https://doi.org/10.1007/BF01936998

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