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Action of homocarnosine, carnosine and anserine on uptake and metabolism of GABA in different subcellular fractions of rat brain

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Summary

L-Carnosine, L-homocarnosine and L-anserine are inhibitors of GABA metabolism. They show differential action on GABA-transaminase from synaptosomes compared to the extrasynaptosomal enzyme.

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Literatur

  1. J.J. Pisano, J.D. Wilson, L. Cohen, D. Abraham and S. Udenfriend, J. biol. Chem.236, 499 (1961).

    PubMed  Google Scholar 

  2. S.E. Severin, J.M. Bocharnikoua, P.L. Vul'fson, Yu.A. Grigorouich and G.A. Solov'eva, Biokhimiya28, 510 (1963).

    Google Scholar 

  3. R.H. Ng, F.D. Marshall, F.A. Henn and A. Sellstrom, J. Neurochem.28, 449 (1977).

    PubMed  Google Scholar 

  4. M. Tardy, B. Rolland, C. Fages and P. Gonnard, Experientia32, 434 (1974).

    Google Scholar 

  5. M. Bloch-Tardy, B. Rolland and P. Gonnard, Biochimie56, 823 (1974).

    PubMed  Google Scholar 

  6. Y. Yoshino, F.V. De Feudis and K.A.C. Elliott, Can. J. Biochem.48, 147 (1970).

    PubMed  Google Scholar 

  7. E. Somoza, M.P. Pugnaire, L.M. Orensanz Muñoz, C.G. Portal, A.E. Ibañez and F.V. De Feudis, J. Neurochem.26, (1977).

  8. E.G. Gray and U.P. Whittaker, J. Anat.96, 79 (1962).

    PubMed  Google Scholar 

  9. M. Israel and P. Frachon Mastour, Archs Anat. microsc.59, 383 (1970).

    Google Scholar 

  10. O.H. Lowry, N.J. Rosebrough, A.L. Farr and R.J. Randall, J. biol. Chem.193, 265 (1951).

    PubMed  Google Scholar 

  11. I.A. Sytinsky and U.Y. Vasiliev, Enzymologia39, 1 (1969).

    Google Scholar 

  12. E. Roberts and D.G. Simonsen, Biochem. Pharmac.12 (2), 113 (1963).

    Google Scholar 

  13. Dixon, Biochem. J.129, 197 (1972).

    PubMed  Google Scholar 

  14. Buu Nguyen and N.M. van Gelder, Can. J. Physiol.52, 674 (1973).

    Google Scholar 

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Tardy, M., Rolland, B., Bardakdjian, J. et al. Action of homocarnosine, carnosine and anserine on uptake and metabolism of GABA in different subcellular fractions of rat brain. Experientia 34, 823–824 (1978). https://doi.org/10.1007/BF01939640

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  • DOI: https://doi.org/10.1007/BF01939640

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